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Prostate, endometrial and thyroid cancers along with several malignant gliomas, breast and urothelial cancers showed moderate to strong cytoplasmic positivity. Remaining malignant cells were in general weakly stained or negative.
GENE INFORMATION
Gene name
JMJD7
Synonyms
Description
Jumonji domain containing 7 (HGNC Symbol)
Entrez gene summary
This gene encodes a highly conserved protein with a JmjC domain, which are part of the cupin metalloenzyme superfamily. JmjC proteins may function as 2-oxoglutarate-Fe(II)-dependent dioxygenases. Most tissues also express read-through transcripts from this gene into the downstream phospholipase A2, group IVB (cytosolic) gene, some of which may encode fusion proteins combining the N-terminus of this protein with the phospholipase A2, group IVB protein. [provided by RefSeq, Jul 2008]
