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Malignant cells in general showed weak cytoplasmic staining or were negative. Most hepatocellular carcinomas along with several lung cancers were moderately stained. Nuclear positivity was observed in a fraction of cells in a few cases, for example in pancreatic and thyroid cancers.
GENE INFORMATION
Gene name
CLRN2
Synonyms
Description
Clarin 2 (HGNC Symbol)
Entrez gene summary
This gene belongs to the clarin family of genes. The clarins appear to belong to a large superfamily of small integral membrane glycoproteins with four transmembrane domains. The exact function of this gene is unknown. [provided by RefSeq, Oct 2008]
