Expression of DCANP1 in cancer - Summary

CANCER ATLAS

Gene description

Dendritic cell-associated nuclear protein

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA048308

GENE INFORMATION
Gene name	DCANP1 (HGNC Symbol)
Synonyms	C5orf20, DCNP1
Description	Dendritic cell-associated nuclear protein (HGNC Symbol)
Entrez gene summary	This intronless gene is specifically expressed in dendritic cells (DCs), which are potent antigen-presenting cells involved in activating naive T cells to initiate antigen-specific immune response. The encoded protein is localized mainly in the perinucleus. One of the alleles (A/T) of this gene, that causes premature translation termination at aa 117, has been associated with an increased prevalence of major depression in humans. [provided by RefSeq, Jul 2008]
Chromosome	5
Cytoband	q31.1
Chromosome location (bp)	135444214 - 135447348
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000251380 (version 83.38)
Entrez gene	140947
UniProt	Q8TF63 (UniProt - Evidence at protein level)
neXtProt	NX_Q8TF63
Antibodypedia	DCANP1 antibodies

PROTEIN BROWSER

DCANP1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DCANP1-001 ENSP00000421871 ENST00000503143	Q8TF63 [Direct mapping] Dendritic cell nuclear protein 1 Show all	Predicted intracellular proteins Show all	GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] Show all	244 aa 26.7 kDa	No	0