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PYDC2

CANCER ATLAS

Gene description

 Pyrin domain containing 2

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA055895

GENE INFORMATION

Gene name

 PYDC2 (HGNC Symbol)

Synonyms

 POP2

Description

 Pyrin domain containing 2 (HGNC Symbol)

Entrez gene summary

Chromosome

 3

Cytoband

 q28

Chromosome location (bp)

 191461163 - 191461456

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000253548 (version 83.38)

Entrez gene

 152138

UniProt

 Q56P42 (UniProt - Evidence at protein level)

neXtProt

 NX_Q56P42

Antibodypedia

 PYDC2 antibodies

PROTEIN BROWSER
PYDC2-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
PYDC2-001
ENSP00000428325
ENST00000518817
Q56P42 [Direct mapping]
Pyrin domain-containing protein 2
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Predicted intracellular proteins
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GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006954 [inflammatory response]
GO:0010804 [negative regulation of tumor necrosis factor-mediated signaling pathway]
GO:0032088 [negative regulation of NF-kappaB transcription factor activity]
GO:0042347 [negative regulation of NF-kappaB import into nucleus]
GO:0045087 [innate immune response]
GO:0050713 [negative regulation of interleukin-1 beta secretion]
GO:0050728 [negative regulation of inflammatory response]
GO:1900226 [negative regulation of NLRP3 inflammasome complex assembly]
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 97 aa
10.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.