Expression of EEF1G in cancer - Summary

CANCER ATLAS

Gene description

Eukaryotic translation elongation factor 1 gamma

Protein class

Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA040688

GENE INFORMATION
Gene name	EEF1G (HGNC Symbol)
Synonyms	EF1G
Description	Eukaryotic translation elongation factor 1 gamma (HGNC Symbol)
Entrez gene summary	This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit contains an N-terminal glutathione transferase domain, which may be involved in regulating the assembly of multisubunit complexes containing this elongation factor and aminoacyl-tRNA synthetases. [provided by RefSeq, Jul 2008]
Chromosome	11
Cytoband	q12.3
Chromosome location (bp)	62559601 - 62574086
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000254772 (version 83.38)
Entrez gene	1937
UniProt	P26641 (UniProt - Evidence at protein level)
neXtProt	NX_P26641
Antibodypedia	EEF1G antibodies

PROTEIN BROWSER

EEF1G-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
EEF1G-001 ENSP00000331901 ENST00000329251	P26641 [Direct mapping] Elongation factor 1-gamma Q53YD7 [Target identity:100%; Query identity:100%] EEF1G protein; Eukaryotic translation elongation factor 1 gamma; Eukaryotic translation elongation factor 1 gamma, isoform CRA_c; GIG35 Show all	MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003746 [translation elongation factor activity] GO:0004364 [glutathione transferase activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005829 [cytosol] GO:0006412 [translation] GO:0006414 [translational elongation] GO:0006749 [glutathione metabolic process] GO:0009615 [response to virus] GO:0010467 [gene expression] GO:0016020 [membrane] GO:0044267 [cellular protein metabolic process] GO:0070062 [extracellular exosome] Show all	437 aa 50.1 kDa	No	0