Expression of ZNF10 in cancer - Summary

CANCER ATLAS

Gene description

Zinc finger protein 10

Protein class

Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA003204

GENE INFORMATION
Gene name	ZNF10 (HGNC Symbol)
Synonyms	KOX1
Description	Zinc finger protein 10 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene contains a C2H2 zinc finger, and has been shown to function as a transcriptional repressor. The Kruppel-associated box (KRAB) domain of this protein is found to be responsible for its transcriptional repression activity. RING finger containing protein TIF1 was reported to interact with the KRAB domain, and may serve as a mediator for the repression activity of this protein. [provided by RefSeq, Jul 2008]
Chromosome	12
Cytoband	q24.33
Chromosome location (bp)	133130575 - 133159465
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000256223 (version 83.38)
Entrez gene	7556
UniProt	P21506 (UniProt - Evidence at protein level)
neXtProt	NX_P21506
Antibodypedia	ZNF10 antibodies

PROTEIN BROWSER

ZNF10-001	ZNF10-002	ZNF10-003	ZNF10-005	ZNF10-007	ZNF10-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF10-001 ENSP00000248211 ENST00000248211	P21506 [Direct mapping] Zinc finger protein 10 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	573 aa 66.5 kDa	No	0
ZNF10-002 ENSP00000393814 ENST00000426665	P21506 [Direct mapping] Zinc finger protein 10 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	573 aa 66.5 kDa	No	0
ZNF10-003 ENSP00000384893 ENST00000402932	F8WD46 [Direct mapping] Zinc finger protein 10 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	439 aa 51.3 kDa	No	0
ZNF10-005 ENSP00000441339 ENST00000536877	F5GZ75 [Direct mapping] Zinc finger protein 10 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	72 aa 8.5 kDa	No	0
ZNF10-007 ENSP00000445997 ENST00000538918	F5H0R3 [Direct mapping] Zinc finger protein 10 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	43 aa 5.2 kDa	No	0
ZNF10-009 ENSP00000438232 ENST00000540609	F5H311 [Direct mapping] Zinc finger protein 10 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	47 aa 5.7 kDa	No	0