Cell atlas - TMEM179 - The Human Protein Atlas

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TMEM179

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS MOUSE CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Mitochondria

Human cell
	Mitochondria

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GENERAL INFORMATION
Gene name	TMEM179
Gene description	Transmembrane protein 179
Protein class	Predicted intracellular proteins Predicted membrane proteins Predicted secreted proteins
Predicted localization	Intracellular,Membrane,Secreted
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the mitochondria.
RNA cell category	Cell line enhanced (SCLC-21H, SH-SY5Y, NTERA-2)
Protein evidence	Evidence at transcript level
Main location	Localized to the Mitochondria (uncertain)
Mouse	Localized to the Mitochondria in mouse cells.

DATA RELIABILITY
Reliability score	Uncertain based on 1 antibody. HPA002942
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (SCLC-21H, SH-SY5Y, NTERA-2) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the mitochondria.

Main location

Mitochondria (uncertain)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA002942	SH-SY5Y	Mitochondria
	HPA002942	U-2 OS	Mitochondria

MOUSE CELLS

Main location

Mitochondria

Mouse gene

ENSMUSG00000054013 (version 83)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location
	HPA002942	NIH 3T3	Mitochondria

GENE INFORMATION
Gene name	TMEM179 (HGNC Symbol)
Synonyms	C14orf90, FLJ42486, TMEM179A
Description	Transmembrane protein 179 (HGNC Symbol)
Entrez gene summary
Chromosome	14
Cytoband	q32.33
Chromosome location (bp)	104474678 - 104605647
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000258986 (version 83.38)
Entrez gene	388021
UniProt	Q6ZVK1 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6ZVK1
Antibodypedia	TMEM179 antibodies

PROTEIN BROWSER

TMEM179-001	TMEM179-002	TMEM179-003	TMEM179-004	TMEM179-201	TMEM179-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TMEM179-001 ENSP00000340477 ENST00000341595	Q6ZVK1 [Direct mapping] Transmembrane protein 179 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	197 aa 21.7 kDa	No	2
TMEM179-002 ENSP00000450958 ENST00000556573	Q6ZVK1 [Direct mapping] Transmembrane protein 179 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	233 aa 26.4 kDa	No	3
TMEM179-003 ENSP00000452113 ENST00000556320	H0YJT8 [Direct mapping] Transmembrane protein 179 Show all	Predicted intracellular proteins Show all		78 aa 7.4 kDa	No	0
TMEM179-004 ENSP00000397763 ENST00000415614	I3L0F2 [Direct mapping] Transmembrane protein 179 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	190 aa 21 kDa	No	2
TMEM179-201 ENSP00000483627 ENST00000615704	A0A087X0S3 [Direct mapping] Transmembrane protein 179 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	211 aa 23.4 kDa	No	2
TMEM179-202 ENSP00000479740 ENST00000616017	Q7Z4P9 [Direct mapping] Transmembrane protein 179 Show all	MEMSAT3 predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all		182 aa 19.6 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.