Tissue expression of TUBB8 - Summary - The Human Protein Atlas

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TUBB8

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	TUBB8
Gene description	Tubulin, beta 8 class VIII
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (testis)

Protein evidence

Evidence at protein level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Caution, targets protein from more than one gene. External characterization data supports antibody staining but no internal RNA data available for correlation.
Reliability score	Uncertain based on 2 antibodies. HPA043640 , HPA046280
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (testis)

GENE INFORMATION
Gene name	TUBB8 (HGNC Symbol)
Synonyms	bA631M21.2
Description	Tubulin, beta 8 class VIII (HGNC Symbol)
Entrez gene summary
Chromosome	10
Cytoband	p15.3
Chromosome location (bp)	46892 - 74163
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000261456 (version 83.38)
Entrez gene	347688
UniProt	Q3ZCM7 (UniProt - Evidence at protein level)
neXtProt	NX_Q3ZCM7
Antibodypedia	TUBB8 antibodies

PROTEIN BROWSER

TUBB8-001	TUBB8-002	TUBB8-005	TUBB8-007	TUBB8-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TUBB8-001 ENSP00000456206 ENST00000568584	Q3ZCM7 [Direct mapping] Tubulin beta-8 chain Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Show all	GO:0003674 [molecular_function] GO:0003924 [GTPase activity] GO:0005200 [structural constituent of cytoskeleton] GO:0005525 [GTP binding] GO:0005737 [cytoplasm] GO:0005874 [microtubule] GO:0007017 [microtubule-based process] GO:0008150 [biological_process] GO:0008152 [metabolic process] GO:0043234 [protein complex] GO:0051258 [protein polymerization] GO:0070062 [extracellular exosome] Show all	444 aa 49.8 kDa	No	0
TUBB8-002 ENSP00000456899 ENST00000562809	A0A075B735 [Direct mapping] Tubulin beta-8 chain Show all	Predicted intracellular proteins Show all	GO:0003924 [GTPase activity] GO:0008152 [metabolic process] Show all	75 aa 7.8 kDa	No	0
TUBB8-005 ENSP00000457610 ENST00000564130	Q5SQY0 [Direct mapping] Tubulin beta-8 chain; Tubulin, beta 8, isoform CRA_c Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0003924 [GTPase activity] GO:0005200 [structural constituent of cytoskeleton] GO:0005525 [GTP binding] GO:0005874 [microtubule] GO:0007017 [microtubule-based process] GO:0008152 [metabolic process] GO:0043234 [protein complex] GO:0051258 [protein polymerization] Show all	410 aa 45.5 kDa	No	0
TUBB8-007 ENSP00000454878 ENST00000561967	A0A075B724 [Direct mapping] Tubulin beta-8 chain Show all	Predicted intracellular proteins Show all	GO:0003924 [GTPase activity] GO:0005200 [structural constituent of cytoskeleton] GO:0005525 [GTP binding] GO:0005874 [microtubule] GO:0007017 [microtubule-based process] GO:0008152 [metabolic process] Show all	119 aa 13 kDa	No	0
TUBB8-008 ENSP00000457062 ENST00000568866	A0A075B736 [Direct mapping] Tubulin beta-8 chain Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0003924 [GTPase activity] GO:0005200 [structural constituent of cytoskeleton] GO:0005525 [GTP binding] GO:0005737 [cytoplasm] GO:0005874 [microtubule] GO:0007017 [microtubule-based process] GO:0008152 [metabolic process] GO:0043234 [protein complex] GO:0051258 [protein polymerization] Show all	407 aa 45.7 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.