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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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MYH4
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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

MYH4

Gene description

Myosin, heavy chain 4, skeletal muscle

Protein class

Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Tissue enriched (skeletal muscle)
GTEx:Tissue enriched (skeletal muscle)
FANTOM5:Not detected

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in skeletal muscle and heart muscle.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data. Caution, targets protein from more than one gene.

Reliability score

Supported based on 1 antibody.
HPA001349
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Skeletal muscle

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (skeletal muscle)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (skeletal muscle)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Not detected

GENE INFORMATION

Gene name

MYH4 (HGNC Symbol)

Synonyms

MYH2B, MyHC-2B, MyHC-IIb

Description

Myosin, heavy chain 4, skeletal muscle (HGNC Symbol)

Entrez gene summary

Chromosome

17

Cytoband

p13.1

Chromosome location (bp)

10443290 - 10469559

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000264424 (version 83.38)

Entrez gene

4622

UniProt

Q9Y623 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y623

Antibodypedia

MYH4 antibodies

PROTEIN BROWSER

MYH4-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MYH4-001
ENSP00000255381
ENST00000255381
Q9Y623 [Direct mapping]
Myosin-4
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Show all
GO:0000146 [microfilament motor activity]
GO:0003725 [double-stranded RNA binding]
GO:0003774 [motor activity]
GO:0003779 [actin binding]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005524 [ATP binding]
GO:0005859 [muscle myosin complex]
GO:0006936 [muscle contraction]
GO:0014823 [response to activity]
GO:0016459 [myosin complex]
GO:0016887 [ATPase activity]
GO:0030016 [myofibril]
GO:0030017 [sarcomere]
GO:0030048 [actin filament-based movement]
GO:0030049 [muscle filament sliding]
GO:0032982 [myosin filament]
GO:0046034 [ATP metabolic process]
GO:0061024 [membrane organization]
Show all
1939 aa
223.1 kDa
No 0

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