Cell atlas - COMMD3-BMI1 - The Human Protein Atlas

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COMMD3-BMI1

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nuclear bodies
	Nucleoli
	Nucleus

Human cell
	Cytosol
	Nucleoli
	Nucleoplasm

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GENERAL INFORMATION
Gene name	COMMD3-BMI1
Gene description	COMMD3-BMI1 readthrough
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nuclear bodies. In addition localized to the nucleus, nucleoli & cytosol. Caution: Based on antibodies targeting proteins from multiple genes.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Nuclear bodies (approved)
Additional location	In addition localized to the Nucleus (approved), Nucleoli (approved), Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 2 antibodies. HPA030471 , HPA030472
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nuclear bodies. In addition localized to the nucleus, nucleoli & cytosol. Caution: Based on antibodies targeting proteins from multiple genes.

Main location

Nuclear bodies (approved)

Additional location

Nucleus (approved), Nucleoli (approved), Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA030471	HEK 293	Nuclear bodies
HPA030471	PC-3	Nuclear bodies
HPA030471	U-2 OS	Nuclear bodies
HPA030471	U-2 OS	Cytosol
HPA030472	A-431	Nucleus
HPA030472	U-2 OS	Nucleus
HPA030472	U-2 OS	Nuclear bodies
HPA030472	U-251 MG	Nucleus
HPA030472	U-251 MG	Nucleoli

GENE INFORMATION
Gene name	COMMD3-BMI1
Synonyms
Description	COMMD3-BMI1 readthrough (HGNC Symbol)
Entrez gene summary	This locus represents naturally occurring read-through transcription between the neighboring COMM domain-containing protein 3 and polycomb complex protein BMI-1 genes on chromosome 10. The read-through transcript produces a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Feb 2011]
Chromosome	10
Cytoband	p12.2
Chromosome location (bp)	22316388 - 22329542
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000269897 (version 83.38)
Entrez gene	100532731
UniProt
neXtProt
Antibodypedia	COMMD3-BMI1 antibodies

PROTEIN BROWSER

COMMD3-BMI1-001	COMMD3-BMI1-004	COMMD3-BMI1-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
COMMD3-BMI1-001 ENSP00000473391 ENST00000602390	R4GMX3 [Direct mapping] Protein COMMD3-BMI1 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0008270 [zinc ion binding] GO:0046872 [metal ion binding] Show all	469 aa 53.3 kDa	No	0
COMMD3-BMI1-004 ENSP00000473382 ENST00000475460	R4GMW6 [Direct mapping] Protein COMMD3-BMI1 Show all	Predicted intracellular proteins Show all		159 aa 18.1 kDa	No	0
COMMD3-BMI1-005 ENSP00000473495 ENST00000489125	R4GN54 [Direct mapping] Protein COMMD3-BMI1 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all		110 aa 12.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.