Tissue expression of CD24 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	CD24
Gene description	CD24 molecule
Protein class	Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (thyroid gland)

Protein evidence

Evidence at transcript level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (thyroid gland)

GENE INFORMATION
Gene name	CD24 (HGNC Symbol)
Synonyms	CD24A
Description	CD24 molecule (HGNC Symbol)
Entrez gene summary	This gene encodes a sialoglycoprotein that is expressed on mature granulocytes and B cells and modulates growth and differentiation signals to these cells. The precursor protein is cleaved to a short 32 amino acid mature peptide which is anchored via a glycosyl phosphatidylinositol (GPI) link to the cell surface. This gene was missing from previous genome assemblies, but is properly located on chromosome 6. Non-transcribed pseudogenes have been designated on chromosomes 1, 15, 20, and Y. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Chromosome	6
Cytoband	q21
Chromosome location (bp)	106969831 - 106975627
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000272398 (version 83.38)
Entrez gene	100133941
UniProt
neXtProt
Antibodypedia	CD24 antibodies

PROTEIN BROWSER

CD24-001	CD24-002	CD24-003	CD24-004	CD24-006	CD24-007	CD24-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CD24-001 ENSP00000483985 ENST00000619133	B6EC88 [Direct mapping] CD24; Signal transducer CD24 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0007155 [cell adhesion] Show all	80 aa 8.1 kDa	Yes	0
CD24-002 ENSP00000483838 ENST00000610952	B6EC88 [Direct mapping] CD24; Signal transducer CD24 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0007155 [cell adhesion] Show all	80 aa 8.1 kDa	Yes	0
CD24-003 ENSP00000478460 ENST00000619869	A0A087WU87 [Direct mapping] Signal transducer CD24 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0007155 [cell adhesion] Show all	88 aa 8.8 kDa	No	0
CD24-004 ENSP00000479895 ENST00000615659	A0A087WW33 [Direct mapping] Signal transducer CD24 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0007155 [cell adhesion] Show all	122 aa 12.5 kDa	No	0
CD24-006 ENSP00000478302 ENST00000620405	A0A087WU21 [Direct mapping] Signal transducer CD24 Show all	MEMSAT3 predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all		37 aa 4.1 kDa	Yes	0
CD24-007 ENSP00000481841 ENST00000622315	A0A087WYI6 [Direct mapping] Signal transducer CD24 Show all	SPOCTOPUS predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all	GO:0001959 [regulation of cytokine-mediated signaling pathway] GO:0002237 [response to molecule of bacterial origin] GO:0002329 [pre-B cell differentiation] GO:0002523 [leukocyte migration involved in inflammatory response] GO:0002842 [positive regulation of T cell mediated immune response to tumor cell] GO:0002863 [positive regulation of inflammatory response to antigenic stimulus] GO:0002904 [positive regulation of B cell apoptotic process] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0006955 [immune response] GO:0007155 [cell adhesion] GO:0007157 [heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules] GO:0007159 [leukocyte cell-cell adhesion] GO:0007166 [cell surface receptor signaling pathway] GO:0007274 [neuromuscular synaptic transmission] GO:0007406 [negative regulation of neuroblast proliferation] GO:0008637 [apoptotic mitochondrial changes] GO:0009897 [external side of plasma membrane] GO:0009986 [cell surface] GO:0010976 [positive regulation of neuron projection development] GO:0016477 [cell migration] GO:0022407 [regulation of cell-cell adhesion] GO:0022409 [positive regulation of cell-cell adhesion] GO:0030246 [carbohydrate binding] GO:0030262 [apoptotic nuclear changes] GO:0030889 [negative regulation of B cell proliferation] GO:0031175 [neuron projection development] GO:0031362 [anchored component of external side of plasma membrane] GO:0031528 [microvillus membrane] GO:0032600 [chemokine receptor transport out of membrane raft] GO:0033625 [positive regulation of integrin activation] GO:0033630 [positive regulation of cell adhesion mediated by integrin] GO:0033632 [regulation of cell-cell adhesion mediated by integrin] GO:0033634 [positive regulation of cell-cell adhesion mediated by integrin] GO:0034107 [negative regulation of erythrocyte clearance] GO:0034109 [homotypic cell-cell adhesion] GO:0034119 [negative regulation of erythrocyte aggregation] GO:0042103 [positive regulation of T cell homeostatic proliferation] GO:0042632 [cholesterol homeostasis] GO:0045577 [regulation of B cell differentiation] GO:0045665 [negative regulation of neuron differentiation] GO:0046014 [negative regulation of T cell homeostatic proliferation] GO:0046641 [positive regulation of alpha-beta T cell proliferation] GO:0048488 [synaptic vesicle endocytosis] GO:0050731 [positive regulation of peptidyl-tyrosine phosphorylation] GO:0050768 [negative regulation of neurogenesis] GO:0050850 [positive regulation of calcium-mediated signaling] GO:0060170 [ciliary membrane] GO:0097190 [apoptotic signaling pathway] Show all	129 aa 13 kDa	No	0
CD24-201 ENSP00000475625 ENST00000606017	B6EC88 [Direct mapping] CD24; Signal transducer CD24 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0007155 [cell adhesion] Show all	80 aa 8.1 kDa	Yes	0