Cell atlas - DGKK - The Human Protein Atlas

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DGKK

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	DGKK
Gene description	Diacylglycerol kinase, kappa
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enriched (Hep G2)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (Hep G2) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	DGKK
Synonyms
Description	Diacylglycerol kinase, kappa (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is an enzyme that phosphorylates diacylglycerol, converting it to phosphatidic acid. The encoded protein is a membrane protein and is inhibited by hydrogen peroxide. Variations in this gene have been associated with hypospadias. [provided by RefSeq, Mar 2011]
Chromosome	X
Cytoband	p11.22
Chromosome location (bp)	50365409 - 50470738
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000274588 (version 83.38)
Entrez gene	139189
UniProt	Q5KSL6 (UniProt - Evidence at protein level)
neXtProt	NX_Q5KSL6
Antibodypedia	DGKK antibodies

PROTEIN BROWSER

DGKK-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DGKK-001 ENSP00000477515 ENST00000611977	Q5KSL6 [Direct mapping] Diacylglycerol kinase kappa Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0004143 [diacylglycerol kinase activity] GO:0005524 [ATP binding] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0006979 [response to oxidative stress] GO:0007205 [protein kinase C-activating G-protein coupled receptor signaling pathway] GO:0007596 [blood coagulation] GO:0016301 [kinase activity] GO:0016310 [phosphorylation] GO:0030168 [platelet activation] GO:0035556 [intracellular signal transduction] GO:0046339 [diacylglycerol metabolic process] GO:0046872 [metal ion binding] Show all	1271 aa 141.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.