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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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TCEB3CL2
  • TISSUE

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  • CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

CANCER ATLAS

Gene description

Transcription elongation factor B polypeptide 3C-like 2

Protein class

Predicted intracellular proteins

Protein evidence

No evidence
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer

STAINING SUMMARY

HPA048971
HPA049178
HPA050086

Tissue

Cancer staining

Breast cancer
Carcinoid
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lymphoma
 

Tissue

Cancer staining

Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer

Staining summary

A few renal cancers displayed strong cytoplasmic while a fraction of tumor cells in a few endometrial cancers exhibited moderate granular cytoplasmic positivity. Remaining cancer cells were negative.

Tissue

Cancer staining

Breast cancer
Carcinoid
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lymphoma
 

Tissue

Cancer staining

Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer

Staining summary

Most cancer tissues showed weak to moderate cytoplasmic staining with additional nuclear positivity in several cases. Several gliomas, lymphomas, melanomas, lung and renal cell carcinomas were negative.

Tissue

Cancer staining

Breast cancer
Carcinoid
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lymphoma
 

Tissue

Cancer staining

Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer

Staining summary

Most cancer tissues showed weak to moderate nuclear immunoreactivity with additional cytoplasmic positivity in a few cases. Occasional pancreatic cancers were strongly stained. Gliomas, non-Hodgkin's lymphomas, testicular, renal breast and prostate cancers were generally negative.

GENE INFORMATION

Gene name

TCEB3CL2

Synonyms

Description

Transcription elongation factor B polypeptide 3C-like 2 (HGNC Symbol)

Entrez gene summary

Chromosome

18

Cytoband

q21.1

Chromosome location (bp)

46962768 - 46964408

Protein evidence

No evidence (all genes)

Ensembl

ENSG00000274744 (version 83.38)

Entrez gene

100506888

UniProt

A6NLF2 (UniProt - Inferred from homology)

neXtProt

NX_A6NLF2

Antibodypedia

TCEB3CL2 antibodies

PROTEIN BROWSER

TCEB3CL2-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TCEB3CL2-001
ENSP00000483981
ENST00000620881
A6NLF2 [Direct mapping]
RNA polymerase II transcription factor SIII subunit A3-like-2
Show all
Predicted intracellular proteins
Show all
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0016021 [integral component of membrane]
Show all
546 aa
59.8 kDa
No 0

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.