Cell atlas - ZNF2 - The Human Protein Atlas

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ZNF2

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nucleoplasm
	Plasma membrane

Human cell
	Cytosol
	Nucleoplasm
	Plasma Membrane

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GENERAL INFORMATION
Gene name	ZNF2
Gene description	Zinc finger protein 2
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the plasma membrane & cytosol. In addition localized to the nucleoplasm.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Plasma membrane (approved), Cytosol (approved)
Additional location	In addition localized to the Nucleoplasm (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA041358
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the plasma membrane & cytosol. In addition localized to the nucleoplasm.

Main location

Plasma membrane (approved), Cytosol (approved)

Additional location

Nucleoplasm (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA041358	A-431	Nucleoplasm
	HPA041358	A-431	Cytosol
	HPA041358	U-2 OS	Plasma membrane
	HPA041358	U-2 OS	Cytosol
	HPA041358	U-251 MG	Nucleoplasm
			Plasma membrane
			Cytosol

GENE INFORMATION
Gene name	ZNF2 (HGNC Symbol)
Synonyms	A1-5, Zfp661, ZNF661
Description	Zinc finger protein 2 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene belongs to the C2H2-type zinc-finger protein family. The exact function of this gene is not known, however, zinc-finger proteins are known to interact with DNA and function as transcription regulators. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
Chromosome	2
Cytoband	q11.1
Chromosome location (bp)	95165432 - 95184317
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000275111 (version 83.38)
Entrez gene	7549
UniProt	Q9BSG1 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BSG1
Antibodypedia	ZNF2 antibodies

PROTEIN BROWSER

ZNF2-001	ZNF2-002	ZNF2-003	ZNF2-004	ZNF2-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF2-001 ENSP00000480297 ENST00000614034	Q9BSG1 [Direct mapping] Zinc finger protein 2 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008270 [zinc ion binding] GO:0046872 [metal ion binding] Show all	425 aa 48.7 kDa	No	0
ZNF2-002 ENSP00000482030 ENST00000611147	A0A087WYR5 [Direct mapping] Zinc finger protein 2 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	438 aa 50.2 kDa	No	0
ZNF2-003 ENSP00000480057 ENST00000617923	B0AZN8 [Direct mapping] Zinc finger protein 2; Zinc finger protein 2, isoform CRA_a; cDNA, FLJ79478, highly similar to Homo sapiens zinc finger protein 2 (ZNF2), transcript variant 1, mRNA Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	383 aa 43.9 kDa	No	0
ZNF2-004 ENSP00000477960 ENST00000611463	Q68CY6 [Direct mapping] Putative uncharacterized protein DKFZp686D2168; Zinc finger protein 2 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0046872 [metal ion binding] Show all	345 aa 39.5 kDa	No	0
ZNF2-005 ENSP00000483131 ENST00000622059	A0A087X063 [Direct mapping] Zinc finger protein 2 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	387 aa 44.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.