Cell atlas - HIST1H2AK - The Human Protein Atlas

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HIST1H2AK

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TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	HIST1H2AK
Gene description	Histone cluster 1, H2ak
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (SCLC-21H, U-266/84, AN3-CA, A549)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (SCLC-21H, U-266/84, AN3-CA, A549) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	HIST1H2AK (HGNC Symbol)
Synonyms	H2A/d, H2AFD
Description	Histone cluster 1, H2ak (HGNC Symbol)
Entrez gene summary	Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]
Chromosome	6
Cytoband	p22.1
Chromosome location (bp)	27837947 - 27838339
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000275221 (version 83.38)
Entrez gene	8330
UniProt	P0C0S8 (UniProt - Evidence at protein level)
neXtProt	NX_P0C0S8
Antibodypedia	HIST1H2AK antibodies

PROTEIN BROWSER

HIST1H2AK-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HIST1H2AK-001 ENSP00000482431 ENST00000618958	P0C0S8 [Direct mapping] Histone H2A type 1 A4FTV9 [Target identity:100%; Query identity:100%] Histone H2A Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0000786 [nucleosome] GO:0000790 [nuclear chromatin] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006325 [chromatin organization] GO:0006342 [chromatin silencing] GO:0008150 [biological_process] GO:0019899 [enzyme binding] GO:0046982 [protein heterodimerization activity] GO:0070062 [extracellular exosome] Show all	130 aa 14.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.