Cell atlas - CAPS - The Human Protein Atlas

GENERAL INFORMATION
Gene name	CAPS
Gene description	Calcyphosine
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the cytosol. In addition localized to the nucleus & plasma membrane. Caution: Based on antibodies targeting proteins from multiple genes.
RNA cell category	Cell line enhanced (SK-BR-3, U-251 MG, U-87 MG)
Protein evidence	Evidence at protein level
Main location	Localized to the Cytosol (supported)
Additional location	In addition localized to the Nucleus (approved), Plasma membrane (approved)
Single-cell variation	Single-cell variation in protein expression observed.

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA043520
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (SK-BR-3, U-251 MG, U-87 MG) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the cytosol. In addition localized to the nucleus & plasma membrane. Caution: Based on antibodies targeting proteins from multiple genes.

Main location

Cytosol (supported)

Additional location

Nucleus (approved), Plasma membrane (approved)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location	Single-cell variation
HPA043520	A-431	Cytosol
HPA043520	U-2 OS	Cytosol
HPA043520	U-251 MG	Nucleus
		Plasma membrane	Intensity
		Cytosol

GENE INFORMATION
Gene name	CAPS (HGNC Symbol)
Synonyms	CAPS1, MGC126562
Description	Calcyphosine (HGNC Symbol)
Entrez gene summary	This gene encodes a calcium-binding protein, which may play a role in the regulation of ion transport. A similar protein was first described as a potentially important regulatory protein in the dog thyroid and was termed as R2D5 antigen in rabbit. Alternative splicing of this gene generates two transcript variants. [provided by RefSeq, Jul 2008]
Chromosome	19
Cytoband	p13.3
Chromosome location (bp)	5914407 - 5915322
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000283027 (version 83.38)
Entrez gene	828
UniProt	Q13938 (UniProt - Evidence at protein level)
neXtProt	NX_Q13938
Antibodypedia	CAPS antibodies

PROTEIN BROWSER

CAPS-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CAPS-202 ENSP00000222125 ENST00000222125	Q13938 [Direct mapping] Calcyphosin Show all	Predicted intracellular proteins Show all	GO:0005509 [calcium ion binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0031982 [vesicle] GO:0035556 [intracellular signal transduction] GO:0070062 [extracellular exosome] GO:0098779 [mitophagy in response to mitochondrial depolarization] Show all	162 aa 17.8 kDa	No	0