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A majority of malignant cells displayed weak to moderate cytoplasmic positivity, often accompanied with membranous staining. Many cases of malignant lymphomas, endometrial and gastric cancers were negative.
A majority of malignant cells displayed weak to moderate cytoplasmic and sometimes nuclear immunoreactivity. A few cases of breast cancers were strongly stained.
GENE INFORMATION
Gene name
ARHGAP33 (HGNC Symbol)
Synonyms
FLJ39019, SNX26, TCGAP
Description
Rho GTPase activating protein 33 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Alternative splice variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010]