Cell atlas - CIAPIN1 - The Human Protein Atlas

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CIAPIN1

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TISSUE

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CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Mitochondria

Human cell
	Mitochondria

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GENERAL INFORMATION
Gene name	CIAPIN1
Gene description	Cytokine induced apoptosis inhibitor 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	9
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the mitochondria.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Mitochondria (supported)
Single-cell variation	Single-cell variation in protein expression observed.

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA041350
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the mitochondria.

Main location

Mitochondria (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA041350	A-431	Nucleoplasm
	HPA041350	A-431	Mitochondria	Intensity
	HPA041350	U-2 OS	Nucleoplasm
	HPA041350	U-2 OS	Mitochondria
	HPA041350	U-251 MG	Nucleoplasm
	HPA041350	U-251 MG	Mitochondria

GENE INFORMATION
Gene name	CIAPIN1 (HGNC Symbol)
Synonyms	Anamorsin
Description	Cytokine induced apoptosis inhibitor 1 (HGNC Symbol)
Entrez gene summary	CIAPIN1 is a cytokine-induced inhibitor of apoptosis with no relation to apoptosis regulatory molecules of the BCL2 (MIM 151430) or CASP (see MIM 147678) families. Expression of CIAPIN1 is dependent on growth factor stimulation (Shibayama et al., 2004 [PubMed 14970183]).[supplied by OMIM, Mar 2008]
Chromosome	16
Cytoband	q21
Chromosome location (bp)	57428169 - 57447528
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000005194 (version 83.38)
Entrez gene	57019
UniProt	Q6FI81 (UniProt - Evidence at protein level)
neXtProt	NX_Q6FI81
Antibodypedia	CIAPIN1 antibodies

PROTEIN BROWSER

CIAPIN1-001	CIAPIN1-002	CIAPIN1-003	CIAPIN1-004	CIAPIN1-010	CIAPIN1-011	CIAPIN1-013	CIAPIN1-015	CIAPIN1-016

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CIAPIN1-001 ENSP00000377914 ENST00000394391	Q6FI81 [Direct mapping] Anamorsin Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0005758 [mitochondrial intermembrane space] GO:0006915 [apoptotic process] GO:0008168 [methyltransferase activity] GO:0009055 [electron carrier activity] GO:0016226 [iron-sulfur cluster assembly] GO:0030097 [hemopoiesis] GO:0032259 [methylation] GO:0043066 [negative regulation of apoptotic process] GO:0044281 [small molecule metabolic process] GO:0046872 [metal ion binding] GO:0051536 [iron-sulfur cluster binding] GO:0051537 [2 iron, 2 sulfur cluster binding] Show all	312 aa 33.6 kDa	No	0
CIAPIN1-002 ENSP00000457042 ENST00000569370	H3BT65 [Direct mapping] Anamorsin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0008168 [methyltransferase activity] GO:0016226 [iron-sulfur cluster assembly] GO:0032259 [methylation] GO:0051536 [iron-sulfur cluster binding] Show all	266 aa 28.9 kDa	No	0
CIAPIN1-003 ENSP00000455309 ENST00000565961	H3BPG7 [Direct mapping] Anamorsin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0008168 [methyltransferase activity] GO:0016226 [iron-sulfur cluster assembly] GO:0032259 [methylation] GO:0051536 [iron-sulfur cluster binding] Show all	239 aa 26.1 kDa	No	0
CIAPIN1-004 ENSP00000456114 ENST00000567518	Q6FI81 [Direct mapping] Anamorsin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0005758 [mitochondrial intermembrane space] GO:0006915 [apoptotic process] GO:0008168 [methyltransferase activity] GO:0009055 [electron carrier activity] GO:0016226 [iron-sulfur cluster assembly] GO:0030097 [hemopoiesis] GO:0032259 [methylation] GO:0043066 [negative regulation of apoptotic process] GO:0044281 [small molecule metabolic process] GO:0046872 [metal ion binding] GO:0051536 [iron-sulfur cluster binding] GO:0051537 [2 iron, 2 sulfur cluster binding] Show all	299 aa 32.2 kDa	No	0
CIAPIN1-010 ENSP00000458000 ENST00000569979	H3BV90 [Direct mapping] Anamorsin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0006915 [apoptotic process] GO:0008168 [methyltransferase activity] GO:0016226 [iron-sulfur cluster assembly] GO:0032259 [methylation] GO:0046872 [metal ion binding] GO:0051536 [iron-sulfur cluster binding] GO:0051537 [2 iron, 2 sulfur cluster binding] Show all	246 aa 26.4 kDa	No	0
CIAPIN1-011 ENSP00000457318 ENST00000565786	H3BTT4 [Direct mapping] Anamorsin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0006915 [apoptotic process] GO:0016226 [iron-sulfur cluster assembly] GO:0046872 [metal ion binding] GO:0051536 [iron-sulfur cluster binding] GO:0051537 [2 iron, 2 sulfur cluster binding] Show all	49 aa 5.3 kDa	No	0
CIAPIN1-013 ENSP00000457400 ENST00000567751	H3BTZ8 [Direct mapping] Anamorsin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0006915 [apoptotic process] GO:0016226 [iron-sulfur cluster assembly] GO:0046872 [metal ion binding] GO:0051536 [iron-sulfur cluster binding] GO:0051537 [2 iron, 2 sulfur cluster binding] Show all	72 aa 7.9 kDa	No	0
CIAPIN1-015 ENSP00000455572 ENST00000563341	H3BQ23 [Direct mapping] Anamorsin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0008152 [metabolic process] GO:0008168 [methyltransferase activity] GO:0016226 [iron-sulfur cluster assembly] GO:0032259 [methylation] GO:0051536 [iron-sulfur cluster binding] Show all	129 aa 13.6 kDa	No	0
CIAPIN1-016 ENSP00000454480 ENST00000568940	H3BT65 [Direct mapping] Anamorsin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0008168 [methyltransferase activity] GO:0016226 [iron-sulfur cluster assembly] GO:0032259 [methylation] GO:0051536 [iron-sulfur cluster binding] Show all	266 aa 28.9 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.