Expression of RHBDD2 in cancer - Summary - The Human Protein Atlas

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RHBDD2

TISSUE

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CELL

CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

CANCER ATLAS

Gene description

Rhomboid domain containing 2

Protein class

Enzymes, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Melanoma

STAINING SUMMARY

HPA051960

GENE INFORMATION
Gene name	RHBDD2 (HGNC Symbol)
Synonyms	NPD007, RHBDL7
Description	Rhomboid domain containing 2 (HGNC Symbol)
Entrez gene summary
Chromosome	7
Cytoband	q11.23
Chromosome location (bp)	75842602 - 75888926
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000005486 (version 83.38)
Entrez gene	57414
UniProt	Q6NTF9 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6NTF9
Antibodypedia	RHBDD2 antibodies

PROTEIN BROWSER

RHBDD2-001	RHBDD2-002	RHBDD2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RHBDD2-001 ENSP00000006777 ENST00000006777	Q6NTF9 [Direct mapping] Rhomboid domain-containing protein 2 Show all	Enzymes Peptidases Serine-type peptidases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0004252 [serine-type endopeptidase activity] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005794 [Golgi apparatus] GO:0006508 [proteolysis] GO:0016021 [integral component of membrane] GO:0048471 [perinuclear region of cytoplasm] Show all	364 aa 39.2 kDa	No	4
RHBDD2-002 ENSP00000391232 ENST00000428119	Q6NTF9 [Direct mapping] Rhomboid domain-containing protein 2 Show all	Enzymes Peptidases Serine-type peptidases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0004252 [serine-type endopeptidase activity] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005794 [Golgi apparatus] GO:0006508 [proteolysis] GO:0016021 [integral component of membrane] Show all	223 aa 23.7 kDa	No	1
RHBDD2-201 ENSP00000314144 ENST00000318622	Q6NTF9 [Direct mapping] Rhomboid domain-containing protein 2 Show all	Enzymes Peptidases Serine-type peptidases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004252 [serine-type endopeptidase activity] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005794 [Golgi apparatus] GO:0006508 [proteolysis] GO:0016021 [integral component of membrane] Show all	223 aa 23.7 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.