Expression of YBX2 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Y box binding protein 2

Protein class

Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA053904	HPA056744	CAB012332

GENE INFORMATION
Gene name	YBX2 (HGNC Symbol)
Synonyms	Contrin, CSDA3, MSY2
Description	Y box binding protein 2 (HGNC Symbol)
Entrez gene summary	This gene encodes a nucleic acid binding protein which is highly expressed in germ cells. The encoded protein binds to a Y-box element in the promoters of certain genes but also binds to mRNA transcribed from these genes. Pseudogenes for this gene are located on chromosome 10 and 15. [provided by RefSeq, Feb 2012]
Chromosome	17
Cytoband	p13.1
Chromosome location (bp)	7288252 - 7294615
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000006047 (version 83.38)
Entrez gene	51087
UniProt	Q9Y2T7 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y2T7
Antibodypedia	YBX2 antibodies

PROTEIN BROWSER

YBX2-001	YBX2-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
YBX2-001 ENSP00000007699 ENST00000007699	Q9Y2T7 [Direct mapping] Y-box-binding protein 2 Show all	Predicted intracellular proteins Transcription factors beta-Barrel DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0003682 [chromatin binding] GO:0003729 [mRNA binding] GO:0003730 [mRNA 3'-UTR binding] GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0005844 [polysome] GO:0006355 [regulation of transcription, DNA-templated] GO:0006366 [transcription from RNA polymerase II promoter] GO:0007283 [spermatogenesis] GO:0007286 [spermatid development] GO:0008289 [lipid binding] GO:0009386 [translational attenuation] GO:0017148 [negative regulation of translation] GO:0030529 [ribonucleoprotein complex] GO:0043021 [ribonucleoprotein complex binding] GO:0045182 [translation regulator activity] GO:0048255 [mRNA stabilization] GO:0048477 [oogenesis] GO:0048599 [oocyte development] GO:0051100 [negative regulation of binding] Show all	364 aa 38.5 kDa	No	0
YBX2-007 ENSP00000459587 ENST00000571464	I3L2D6 [Direct mapping] Y-box-binding protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		164 aa 18.4 kDa	No	0