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YBX2

GENERAL INFORMATION

Gene name

 YBX2

Gene description

 Y box binding protein 2

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (testis)
GTEx:Tissue enriched (testis)
FANTOM5:Tissue enriched (testis)

Protein evidence

 Evidence at protein level

Protein expression

 Selective cytoplasmic expression in testis.

DATA RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data.

Reliability score

 Supported based on 3 antibodies.
HPA053904 , HPA056744 , CAB012332
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)

GENE INFORMATION

Gene name

 YBX2 (HGNC Symbol)

Synonyms

 Contrin, CSDA3, MSY2

Description

 Y box binding protein 2 (HGNC Symbol)

Entrez gene summary

 This gene encodes a nucleic acid binding protein which is highly expressed in germ cells. The encoded protein binds to a Y-box element in the promoters of certain genes but also binds to mRNA transcribed from these genes. Pseudogenes for this gene are located on chromosome 10 and 15. [provided by RefSeq, Feb 2012]

Chromosome

 17

Cytoband

 p13.1

Chromosome location (bp)

 7288252 - 7294615

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000006047 (version 83.38)

Entrez gene

 51087

UniProt

 Q9Y2T7 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9Y2T7

Antibodypedia

 YBX2 antibodies

PROTEIN BROWSER
YBX2-001
YBX2-007

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
YBX2-001
ENSP00000007699
ENST00000007699
Q9Y2T7 [Direct mapping]
Y-box-binding protein 2
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Predicted intracellular proteins
Transcription factors
   beta-Barrel DNA-binding domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0003677 [DNA binding]
GO:0003682 [chromatin binding]
GO:0003729 [mRNA binding]
GO:0003730 [mRNA 3'-UTR binding]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005844 [polysome]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007283 [spermatogenesis]
GO:0007286 [spermatid development]
GO:0008289 [lipid binding]
GO:0009386 [translational attenuation]
GO:0017148 [negative regulation of translation]
GO:0030529 [ribonucleoprotein complex]
GO:0043021 [ribonucleoprotein complex binding]
GO:0045182 [translation regulator activity]
GO:0048255 [mRNA stabilization]
GO:0048477 [oogenesis]
GO:0048599 [oocyte development]
GO:0051100 [negative regulation of binding]
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 364 aa
38.5 kDa 		No 0
YBX2-007
ENSP00000459587
ENST00000571464
I3L2D6 [Direct mapping]
Y-box-binding protein 2
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 164 aa
18.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.