Tissue expression of PHF7 - Summary - The Human Protein Atlas

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PHF7

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TISSUE

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CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	PHF7
Gene description	PHD finger protein 7
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (testis)
GTEx:	Tissue enriched (testis)
FANTOM5:	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression

Selective expression in testis.

DATA RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Presumed off target binding observed and disregarded.
Reliability score	Supported based on 2 antibodies. HPA036283 , HPA070305
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)

GENE INFORMATION
Gene name	PHF7 (HGNC Symbol)
Synonyms	HSPC226, NYD-SP6
Description	PHD finger protein 7 (HGNC Symbol)
Entrez gene summary	Spermatogenesis is a complex process regulated by extracellular and intracellular factors as well as cellular interactions among interstitial cells of the testis, Sertoli cells, and germ cells. This gene is expressed in the testis in Sertoli cells but not germ cells. The protein encoded by this gene contains plant homeodomain (PHD) finger domains, also known as leukemia associated protein (LAP) domains, believed to be involved in transcriptional regulation. The protein, which localizes to the nucleus of transfected cells, has been implicated in the transcriptional regulation of spermatogenesis. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
Chromosome	3
Cytoband	p21.1
Chromosome location (bp)	52410561 - 52423641
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000010318 (version 83.38)
Entrez gene	51533
UniProt	Q9BWX1 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BWX1
Antibodypedia	PHF7 antibodies

PROTEIN BROWSER

PHF7-001	PHF7-004	PHF7-010	PHF7-011	PHF7-201	PHF7-202	PHF7-203

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PHF7-001 ENSP00000333024 ENST00000327906	Q9BWX1 [Direct mapping] PHD finger protein 7 A0A024R336 [Target identity:100%; Query identity:100%] PHD finger protein 7, isoform CRA_a Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005815 [microtubule organizing center] GO:0008270 [zinc ion binding] Show all	381 aa 43.8 kDa	No	0
PHF7-004 ENSP00000246282 ENST00000347025	Q9BWX1 [Direct mapping] PHD finger protein 7 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005815 [microtubule organizing center] GO:0008270 [zinc ion binding] Show all	342 aa 39.3 kDa	No	0
PHF7-010 ENSP00000420521 ENST00000465863	H7C5Q8 [Direct mapping] PHD finger protein 7 Show all	Predicted intracellular proteins Show all		63 aa 7.4 kDa	No	0
PHF7-011 ENSP00000417712 ENST00000461861	H7C4N0 [Direct mapping] PHD finger protein 7 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0008270 [zinc ion binding] Show all	326 aa 37.4 kDa	No	0
PHF7-201 ENSP00000480003 ENST00000614886	Q9BWX1 [Direct mapping] PHD finger protein 7 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005815 [microtubule organizing center] GO:0008270 [zinc ion binding] Show all	342 aa 39.3 kDa	No	0
PHF7-202 ENSP00000483724 ENST00000615126	A0A087X0X8 [Direct mapping] PHD finger protein 7 Show all	Predicted intracellular proteins Show all		213 aa 23.9 kDa	No	0
PHF7-203 ENSP00000478693 ENST00000620464	A0A087WUI3 [Direct mapping] PHD finger protein 7 Show all	Predicted intracellular proteins Show all		248 aa 28 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.