Tissue expression of NCAPH2 - Summary - The Human Protein Atlas

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NCAPH2

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TISSUE

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CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	NCAPH2
Gene description	Non-SMC condensin II complex, subunit H2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Nuclear expression in proliferating cells.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Supported based on 1 antibody. HPA069056
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	NCAPH2 (HGNC Symbol)
Synonyms	384D8-2, CAP-H2, hCAP-H2
Description	Non-SMC condensin II complex, subunit H2 (HGNC Symbol)
Entrez gene summary	This gene encodes one of the non-SMC subunits of the condensin II complex. This complex plays an essential role in mitotic chromosome assembly. Alternate splicing of this gene results in multiple transcript variants.[provided by RefSeq, May 2010]
Chromosome	22
Cytoband	q13.33
Chromosome location (bp)	50508216 - 50523472
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000025770 (version 83.38)
Entrez gene	29781
UniProt	Q6IBW4 (UniProt - Evidence at protein level)
neXtProt	NX_Q6IBW4
Antibodypedia	NCAPH2 antibodies

PROTEIN BROWSER

NCAPH2-001	NCAPH2-003	NCAPH2-006	NCAPH2-009	NCAPH2-012	NCAPH2-016

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NCAPH2-001 ENSP00000410088 ENST00000420993	Q6IBW4 [Direct mapping] Condensin-2 complex subunit H2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000278 [mitotic cell cycle] GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005694 [chromosome] GO:0016020 [membrane] GO:0030261 [chromosome condensation] Show all	605 aa 68.2 kDa	No	0
NCAPH2-003 ENSP00000379050 ENST00000395698	Q6IBW4 [Direct mapping] Condensin-2 complex subunit H2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000278 [mitotic cell cycle] GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005694 [chromosome] GO:0016020 [membrane] GO:0030261 [chromosome condensation] Show all	299 aa 32.8 kDa	No	0
NCAPH2-006 ENSP00000379053 ENST00000395701	A0A0A6YYG7 [Direct mapping] Condensin-2 complex subunit H2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		589 aa 66.3 kDa	No	0
NCAPH2-009 ENSP00000299821 ENST00000299821	Q6IBW4 [Direct mapping] Condensin-2 complex subunit H2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000278 [mitotic cell cycle] GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005694 [chromosome] GO:0016020 [membrane] GO:0030261 [chromosome condensation] Show all	606 aa 68.3 kDa	No	0
NCAPH2-012 ENSP00000429025 ENST00000523045	E5RJN3 [Direct mapping] Condensin-2 complex subunit H2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		292 aa 32.2 kDa	No	0
NCAPH2-016 ENSP00000430944 ENST00000522304	H0YC55 [Direct mapping] Condensin-2 complex subunit H2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		141 aa 16 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.