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Several cases of carcinoids, melanomas along with a few cases of gliomas, colorectal, liver and pancreatic cancers showed moderate nuclear/nucleolar positivity. Remaining cancer tissues were weakly stained or negative.
GENE INFORMATION
Gene name
CENPQ (HGNC Symbol)
Synonyms
C6orf139, CENP-Q, FLJ10545
Description
Centromere protein Q (HGNC Symbol)
Entrez gene summary
CENPQ is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006 [PubMed 16622420]).[supplied by OMIM, Mar 2008]