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Most cancer tissues were negative. A few cases of colon, breast and prostate cancers expressed moderate cytoplasmic staining.
GENE INFORMATION
Gene name
GOPC (HGNC Symbol)
Synonyms
CAL, dJ94G16.2, FIG, GOPC1, PIST
Description
Golgi-associated PDZ and coiled-coil motif containing (HGNC Symbol)
Entrez gene summary
This gene encodes a Golgi protein with a PDZ domain. The PDZ domain is globular and proteins which contain them bind other proteins through short motifs near the C-termini. Mice which are deficient in the orthologous protein have globozoospermia and are infertile. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Q9HD26 [Direct mapping] Golgi-associated PDZ and coiled-coil motif-containing protein
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Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Other Mutations Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Q9HD26 [Direct mapping] Golgi-associated PDZ and coiled-coil motif-containing protein
Show all
Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Other Mutations Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
F5H1Y4 [Direct mapping] Golgi-associated PDZ and coiled-coil motif containing protein transcript variant 3; Golgi-associated PDZ and coiled-coil motif-containing protein
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Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Other Mutations Protein evidence (Ezkurdia et al 2014)
