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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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USP13
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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

USP13

Gene description

Ubiquitin specific peptidase 13 (isopeptidase T-3)

Protein class

Enzymes
Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

General cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data. Presumed off target binding observed and disregarded.

Reliability score

Uncertain based on 1 antibody.
HPA004827
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

USP13 (HGNC Symbol)

Synonyms

IsoT-3

Description

Ubiquitin specific peptidase 13 (isopeptidase T-3) (HGNC Symbol)

Entrez gene summary

Chromosome

3

Cytoband

q26.33

Chromosome location (bp)

179652755 - 179789401

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000058056 (version 83.38)

Entrez gene

8975

UniProt

Q92995 (UniProt - Evidence at protein level)

neXtProt

NX_Q92995

Antibodypedia

USP13 antibodies

PROTEIN BROWSER

USP13-001
USP13-003
USP13-006

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

USP13-001
ENSP00000263966
ENST00000263966
Q92995 [Direct mapping]
Ubiquitin carboxyl-terminal hydrolase 13
A0A0A6YZ17 [Target identity:100%; Query identity:100%]
Ubiquitin carboxyl-terminal hydrolase
Show all
Enzymes
   ENZYME proteins
   Hydrolases
   Peptidases
   Cysteine-type peptidases
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004197 [cysteine-type endopeptidase activity]
GO:0004843 [ubiquitin-specific protease activity]
GO:0005515 [protein binding]
GO:0005764 [lysosome]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006511 [ubiquitin-dependent protein catabolic process]
GO:0006914 [autophagy]
GO:0008242 [omega peptidase activity]
GO:0008270 [zinc ion binding]
GO:0008283 [cell proliferation]
GO:0010506 [regulation of autophagy]
GO:0016579 [protein deubiquitination]
GO:0030318 [melanocyte differentiation]
GO:0031625 [ubiquitin protein ligase binding]
GO:0036459 [ubiquitinyl hydrolase activity]
GO:0043130 [ubiquitin binding]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0044389 [ubiquitin-like protein ligase binding]
GO:0050821 [protein stabilization]
GO:0051087 [chaperone binding]
GO:0061136 [regulation of proteasomal protein catabolic process]
GO:0070536 [protein K63-linked deubiquitination]
GO:0070628 [proteasome binding]
GO:1904288 [BAT3 complex binding]
GO:1904294 [positive regulation of ERAD pathway]
GO:1904378 [maintenance of unfolded protein involved in ERAD pathway]
GO:1904454 [ubiquitin-specific protease activity involved in positive regulation of ERAD pathway]
Show all
863 aa
97.3 kDa
No 0
USP13-003
ENSP00000417146
ENST00000496897
Q92995 [Direct mapping]
Ubiquitin carboxyl-terminal hydrolase 13
Show all
Enzymes
   ENZYME proteins
   Hydrolases
   Peptidases
   Cysteine-type peptidases
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004197 [cysteine-type endopeptidase activity]
GO:0004843 [ubiquitin-specific protease activity]
GO:0005515 [protein binding]
GO:0005764 [lysosome]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006511 [ubiquitin-dependent protein catabolic process]
GO:0006914 [autophagy]
GO:0008242 [omega peptidase activity]
GO:0008270 [zinc ion binding]
GO:0008283 [cell proliferation]
GO:0010506 [regulation of autophagy]
GO:0016579 [protein deubiquitination]
GO:0030318 [melanocyte differentiation]
GO:0031625 [ubiquitin protein ligase binding]
GO:0036459 [ubiquitinyl hydrolase activity]
GO:0043130 [ubiquitin binding]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0044389 [ubiquitin-like protein ligase binding]
GO:0050821 [protein stabilization]
GO:0051087 [chaperone binding]
GO:0061136 [regulation of proteasomal protein catabolic process]
GO:0070536 [protein K63-linked deubiquitination]
GO:0070628 [proteasome binding]
GO:1904288 [BAT3 complex binding]
GO:1904294 [positive regulation of ERAD pathway]
GO:1904378 [maintenance of unfolded protein involved in ERAD pathway]
GO:1904454 [ubiquitin-specific protease activity involved in positive regulation of ERAD pathway]
Show all
798 aa
90.4 kDa
No 0
USP13-006
ENSP00000420057
ENST00000497155
H7C5J3 [Direct mapping]
Ubiquitin carboxyl-terminal hydrolase 13
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005764 [lysosome]
GO:0016579 [protein deubiquitination]
GO:0036459 [ubiquitinyl hydrolase activity]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0061136 [regulation of proteasomal protein catabolic process]
Show all
299 aa
34.2 kDa
No 0

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The Human Protein Atlas project is funded
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