Expression of ATP2C2 in cancer - Summary

CANCER ATLAS

Gene description

ATPase, Ca++ transporting, type 2C, member 2

Protein class

Enzymes, Predicted membrane proteins, Transporters

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA052262

GENE INFORMATION
Gene name	ATP2C2 (HGNC Symbol)
Synonyms	KIAA0703, SPCA2
Description	ATPase, Ca++ transporting, type 2C, member 2 (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	q24.1
Chromosome location (bp)	84368527 - 84464187
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000064270 (version 83.38)
Entrez gene	9914
UniProt	O75185 (UniProt - Evidence at protein level)
neXtProt	NX_O75185
Antibodypedia	ATP2C2 antibodies

PROTEIN BROWSER

ATP2C2-001	ATP2C2-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ATP2C2-001 ENSP00000262429 ENST00000262429	O75185 [Direct mapping] Calcium-transporting ATPase type 2C member 2 Show all	Enzymes ENZYME proteins Hydrolases Transporters Primary Active Transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0000166 [nucleotide binding] GO:0005388 [calcium-transporting ATPase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005887 [integral component of plasma membrane] GO:0006816 [calcium ion transport] GO:0006874 [cellular calcium ion homeostasis] GO:0008152 [metabolic process] GO:0015410 [manganese-transporting ATPase activity] GO:0016021 [integral component of membrane] GO:0034220 [ion transmembrane transport] GO:0046872 [metal ion binding] GO:0055085 [transmembrane transport] GO:0070588 [calcium ion transmembrane transport] GO:0071421 [manganese ion transmembrane transport] Show all	946 aa 103.2 kDa	No	>9
ATP2C2-002 ENSP00000397925 ENST00000416219	A0A0A0MSP0 [Direct mapping] Calcium-transporting ATPase Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0005388 [calcium-transporting ATPase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0006816 [calcium ion transport] GO:0008152 [metabolic process] GO:0009898 [cytoplasmic side of plasma membrane] GO:0016021 [integral component of membrane] GO:0031410 [cytoplasmic vesicle] GO:0046872 [metal ion binding] GO:0048471 [perinuclear region of cytoplasm] GO:0061180 [mammary gland epithelium development] GO:0070588 [calcium ion transmembrane transport] GO:0072661 [protein targeting to plasma membrane] GO:0090280 [positive regulation of calcium ion import] Show all	975 aa 106.2 kDa	No	>9