We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Cell lines sorted after organ of phenotypic resemblance.
Cell lines sorted after biological source for establishment.
Cell lines sorted after the cell line category according to Cellosaurus.
Cell lines sorted on descending RNA expression.
Cell lines sorted alphabetically.
GENE INFORMATION
Gene name
NTHL1 (HGNC Symbol)
Synonyms
NTH1, OCTS3
Description
Nth-like DNA glycosylase 1 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is a DNA N-glycosylase of the endonuclease III family. Like a similar protein in E. coli, the encoded protein has DNA glycosylase activity on DNA substrates containing oxidized pyrimidine residues and has apurinic/apyrimidinic lyase activity. [provided by RefSeq, Oct 2008]
P78549 [Direct mapping] Endonuclease III-like protein 1 E5KTI5 [Target identity:100%; Query identity:100%] Endonuclease III-like protein 1
Show all
Enzymes ENZYME proteins Lyases Predicted intracellular proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000703 [oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity] GO:0002230 [positive regulation of defense response to virus by host] GO:0003677 [DNA binding] GO:0003690 [double-stranded DNA binding] GO:0003824 [catalytic activity] GO:0003906 [DNA-(apurinic or apyrimidinic site) lyase activity] GO:0004519 [endonuclease activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005739 [mitochondrion] GO:0006281 [DNA repair] GO:0006284 [base-excision repair] GO:0006285 [base-excision repair, AP site formation] GO:0006296 [nucleotide-excision repair, DNA incision, 5'-to lesion] GO:0019104 [DNA N-glycosylase activity] GO:0045008 [depyrimidination] GO:0046872 [metal ion binding] GO:0051539 [4 iron, 4 sulfur cluster binding] GO:0098779 [mitophagy in response to mitochondrial depolarization]
