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Colorectal, urothelial cancers along with several testis, cervical, skin and few cases of pancreas cancers and gliomas showed moderate to strong nucleolar positivity. Other cancer tissues were weakly stained or negative.
Several cases of melanomas, skin, testicular, urothelial and colorectal cancers showed moderate to strong nucleolar positivity. Remaining cancer tissues were weakly stained or negative.
GENE INFORMATION
Gene name
DNTTIP2 (HGNC Symbol)
Synonyms
ERBP, HSU15552, TdIF2
Description
Deoxynucleotidyltransferase, terminal, interacting protein 2 (HGNC Symbol)
Entrez gene summary
This gene is thought to be involved in chromatin remodeling and gene transcription. The encoded nuclear protein binds to and enhances the transcriptional activity of the estrogen receptor alpha, and also interacts with terminal deoxynucleotidyltransferase. The expression profile of this gene is a potential biomarker for chronic obstructive pulmonary disease. [provided by RefSeq, Dec 2010]
