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Most malignant tissues showed moderate nuclear membranous/nuclear staining with additional cytoplasmic positivity in several cases. A few cases of cervical, urothelial and colorectal cancers were strongly stained. Several cases of skin cancers were weakly stained.
GENE INFORMATION
Gene name
TBC1D25 (HGNC Symbol)
Synonyms
OATL1
Description
TBC1 domain family, member 25 (HGNC Symbol)
Entrez gene summary
This gene encodes a protein with a TBC domain and may function as a Rab GTPase activating protein. This gene was previously known as ornithine aminotransferase-like 1, but has no similarity to ornithine aminotransferase. [provided by RefSeq, Jul 2008]