Tissue expression of TBC1D25 - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

TBC1D25

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	TBC1D25
Gene description	TBC1 domain family, member 25
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

General cytoplasmic expression, additional nuclear expression in a few tissues.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA029197
	SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	TBC1D25 (HGNC Symbol)
Synonyms	OATL1
Description	TBC1 domain family, member 25 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein with a TBC domain and may function as a Rab GTPase activating protein. This gene was previously known as ornithine aminotransferase-like 1, but has no similarity to ornithine aminotransferase. [provided by RefSeq, Jul 2008]
Chromosome	X
Cytoband	p11.23
Chromosome location (bp)	48539457 - 48562609
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000068354 (version 83.38)
Entrez gene	4943
UniProt	Q3MII6 (UniProt - Evidence at protein level)
neXtProt	NX_Q3MII6
Antibodypedia	TBC1D25 antibodies

PROTEIN BROWSER

TBC1D25-001	TBC1D25-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TBC1D25-001 ENSP00000365962 ENST00000376771	Q3MII6 [Direct mapping] TBC1 domain family member 25 Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0005515 [protein binding] GO:0005776 [autophagosome] GO:0006914 [autophagy] GO:0031410 [cytoplasmic vesicle] GO:0043547 [positive regulation of GTPase activity] GO:1901096 [regulation of autophagosome maturation] Show all	688 aa 76.3 kDa	No	0
TBC1D25-005 ENSP00000402268 ENST00000418627	C9JMI8 [Direct mapping] TBC1 domain family member 25 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		230 aa 25 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.