Expression of TRPC7 in cancer - Summary

CANCER ATLAS

Gene description

Transient receptor potential cation channel, subfamily C, member 7

Protein class

Predicted membrane proteins, Voltage-gated ion channels

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA031126	CAB022592

GENE INFORMATION
Gene name	TRPC7
Synonyms
Description	Transient receptor potential cation channel, subfamily C, member 7 (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	q31.1
Chromosome location (bp)	136213320 - 136365537
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000069018 (version 83.38)
Entrez gene	57113
UniProt	Q9HCX4 (UniProt - Evidence at protein level)
neXtProt	NX_Q9HCX4
Antibodypedia	TRPC7 antibodies

PROTEIN BROWSER

TRPC7-001	TRPC7-003	TRPC7-005	TRPC7-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TRPC7-001 ENSP00000426070 ENST00000513104	Q9HCX4 [Direct mapping] Short transient receptor potential channel 7 Show all	Voltage-gated ion channels Transient Receptor Potential Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0005216 [ion channel activity] GO:0005262 [calcium channel activity] GO:0005515 [protein binding] GO:0005635 [nuclear envelope] GO:0005801 [cis-Golgi network] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006811 [ion transport] GO:0006816 [calcium ion transport] GO:0006828 [manganese ion transport] GO:0007411 [axon guidance] GO:0007596 [blood coagulation] GO:0015279 [store-operated calcium channel activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0030168 [platelet activation] GO:0034220 [ion transmembrane transport] GO:0048471 [perinuclear region of cytoplasm] GO:0051480 [cytosolic calcium ion homeostasis] GO:0055085 [transmembrane transport] GO:0070588 [calcium ion transmembrane transport] GO:0070679 [inositol 1,4,5 trisphosphate binding] Show all	862 aa 99.6 kDa	No	7
TRPC7-003 ENSP00000330322 ENST00000352189	Q9HCX4 [Direct mapping] Short transient receptor potential channel 7 Show all	Voltage-gated ion channels Transient Receptor Potential Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Show all	GO:0005216 [ion channel activity] GO:0005515 [protein binding] GO:0005635 [nuclear envelope] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006811 [ion transport] GO:0006828 [manganese ion transport] GO:0007411 [axon guidance] GO:0007596 [blood coagulation] GO:0015279 [store-operated calcium channel activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0030168 [platelet activation] GO:0034220 [ion transmembrane transport] GO:0051480 [cytosolic calcium ion homeostasis] GO:0055085 [transmembrane transport] GO:0070588 [calcium ion transmembrane transport] GO:0070679 [inositol 1,4,5 trisphosphate binding] Show all	746 aa 86.3 kDa	No	6
TRPC7-005 ENSP00000367720 ENST00000378459	Q9HCX4 [Direct mapping] Short transient receptor potential channel 7 Show all	Voltage-gated ion channels Transient Receptor Potential Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0005216 [ion channel activity] GO:0005515 [protein binding] GO:0005635 [nuclear envelope] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006811 [ion transport] GO:0006828 [manganese ion transport] GO:0007411 [axon guidance] GO:0007596 [blood coagulation] GO:0015279 [store-operated calcium channel activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0030168 [platelet activation] GO:0034220 [ion transmembrane transport] GO:0051480 [cytosolic calcium ion homeostasis] GO:0055085 [transmembrane transport] GO:0070588 [calcium ion transmembrane transport] GO:0070679 [inositol 1,4,5 trisphosphate binding] Show all	801 aa 92.4 kDa	No	7
TRPC7-006 ENSP00000424854 ENST00000502753	Q70T25 [Direct mapping] Short transient receptor potential channel 7; Transient receptor potential channel 7 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Show all	GO:0005216 [ion channel activity] GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0005887 [integral component of plasma membrane] GO:0006811 [ion transport] GO:0006828 [manganese ion transport] GO:0015279 [store-operated calcium channel activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0051480 [cytosolic calcium ion homeostasis] GO:0055085 [transmembrane transport] GO:0070588 [calcium ion transmembrane transport] GO:0070679 [inositol 1,4,5 trisphosphate binding] Show all	807 aa 93.4 kDa	No	6