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TRPC7

GENERAL INFORMATION

Gene name

 TRPC7

Gene description

 Transient receptor potential cation channel, subfamily C, member 7

Protein class

 Predicted membrane proteins
Voltage-gated ion channels

Predicted localization

 Membrane

Number of transcripts

 4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Not detected
GTEx:Tissue enhanced (testis, pituitary gland)

Protein evidence

 Evidence at protein level

Protein expression

 Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. No RNA expression data detected and pending external verification.

Reliability score

 Uncertain based on 2 antibodies.
HPA031126 , CAB022592
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Not detected
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (testis, pituitary gland)

GENE INFORMATION

Gene name

 TRPC7

Synonyms

Description

 Transient receptor potential cation channel, subfamily C, member 7 (HGNC Symbol)

Entrez gene summary

Chromosome

 5

Cytoband

 q31.1

Chromosome location (bp)

 136213320 - 136365537

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000069018 (version 83.38)

Entrez gene

 57113

UniProt

 Q9HCX4 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9HCX4

Antibodypedia

 TRPC7 antibodies

PROTEIN BROWSER
TRPC7-001
TRPC7-003
TRPC7-005
TRPC7-006

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TRPC7-001
ENSP00000426070
ENST00000513104
Q9HCX4 [Direct mapping]
Short transient receptor potential channel 7
Show all
Voltage-gated ion channels
   Transient Receptor Potential Channels
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   7TM proteins predicted by MDM
Show all
GO:0005216 [ion channel activity]
GO:0005262 [calcium channel activity]
GO:0005515 [protein binding]
GO:0005635 [nuclear envelope]
GO:0005801 [cis-Golgi network]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006811 [ion transport]
GO:0006816 [calcium ion transport]
GO:0006828 [manganese ion transport]
GO:0007411 [axon guidance]
GO:0007596 [blood coagulation]
GO:0015279 [store-operated calcium channel activity]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0030168 [platelet activation]
GO:0034220 [ion transmembrane transport]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051480 [cytosolic calcium ion homeostasis]
GO:0055085 [transmembrane transport]
GO:0070588 [calcium ion transmembrane transport]
GO:0070679 [inositol 1,4,5 trisphosphate binding]
Show all
 862 aa
99.6 kDa 		No 7
TRPC7-003
ENSP00000330322
ENST00000352189
Q9HCX4 [Direct mapping]
Short transient receptor potential channel 7
Show all
Voltage-gated ion channels
   Transient Receptor Potential Channels
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   6TM proteins predicted by MDM
Show all
GO:0005216 [ion channel activity]
GO:0005515 [protein binding]
GO:0005635 [nuclear envelope]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006811 [ion transport]
GO:0006828 [manganese ion transport]
GO:0007411 [axon guidance]
GO:0007596 [blood coagulation]
GO:0015279 [store-operated calcium channel activity]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0030168 [platelet activation]
GO:0034220 [ion transmembrane transport]
GO:0051480 [cytosolic calcium ion homeostasis]
GO:0055085 [transmembrane transport]
GO:0070588 [calcium ion transmembrane transport]
GO:0070679 [inositol 1,4,5 trisphosphate binding]
Show all
 746 aa
86.3 kDa 		No 6
TRPC7-005
ENSP00000367720
ENST00000378459
Q9HCX4 [Direct mapping]
Short transient receptor potential channel 7
Show all
Voltage-gated ion channels
   Transient Receptor Potential Channels
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   7TM proteins predicted by MDM
Show all
GO:0005216 [ion channel activity]
GO:0005515 [protein binding]
GO:0005635 [nuclear envelope]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006811 [ion transport]
GO:0006828 [manganese ion transport]
GO:0007411 [axon guidance]
GO:0007596 [blood coagulation]
GO:0015279 [store-operated calcium channel activity]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0030168 [platelet activation]
GO:0034220 [ion transmembrane transport]
GO:0051480 [cytosolic calcium ion homeostasis]
GO:0055085 [transmembrane transport]
GO:0070588 [calcium ion transmembrane transport]
GO:0070679 [inositol 1,4,5 trisphosphate binding]
Show all
 801 aa
92.4 kDa 		No 7
TRPC7-006
ENSP00000424854
ENST00000502753
Q70T25 [Direct mapping]
Short transient receptor potential channel 7; Transient receptor potential channel 7
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   6TM proteins predicted by MDM
Show all
GO:0005216 [ion channel activity]
GO:0005515 [protein binding]
GO:0005829 [cytosol]
GO:0005887 [integral component of plasma membrane]
GO:0006811 [ion transport]
GO:0006828 [manganese ion transport]
GO:0015279 [store-operated calcium channel activity]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0051480 [cytosolic calcium ion homeostasis]
GO:0055085 [transmembrane transport]
GO:0070588 [calcium ion transmembrane transport]
GO:0070679 [inositol 1,4,5 trisphosphate binding]
Show all
 807 aa
93.4 kDa 		No 6

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.