Expression of TRIP13 in cancer - Summary

CANCER ATLAS

Gene description

Thyroid hormone receptor interactor 13

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA005727	HPA053093

GENE INFORMATION
Gene name	TRIP13 (HGNC Symbol)
Synonyms	16E1BP
Description	Thyroid hormone receptor interactor 13 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein that interacts with thyroid hormone receptors, also known as hormone-dependent transcription factors. The gene product interacts specifically with the ligand binding domain. This gene is one of several that may play a role in early-stage non-small cell lung cancer. [provided by RefSeq, Oct 2009]
Chromosome	5
Cytoband	p15.33
Chromosome location (bp)	892643 - 919357
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000071539 (version 83.38)
Entrez gene	9319
UniProt	Q15645 (UniProt - Evidence at protein level)
neXtProt	NX_Q15645
Antibodypedia	TRIP13 antibodies

PROTEIN BROWSER

TRIP13-001	TRIP13-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TRIP13-001 ENSP00000166345 ENST00000166345	Q15645 [Direct mapping] Pachytene checkpoint protein 2 homolog Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001556 [oocyte maturation] GO:0001673 [male germ cell nucleus] GO:0003712 [transcription cofactor activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0006302 [double-strand break repair] GO:0006366 [transcription from RNA polymerase II promoter] GO:0007130 [synaptonemal complex assembly] GO:0007131 [reciprocal meiotic recombination] GO:0007141 [male meiosis I] GO:0007144 [female meiosis I] GO:0007283 [spermatogenesis] GO:0007286 [spermatid development] GO:0042802 [identical protein binding] GO:0048477 [oogenesis] GO:1903506 [regulation of nucleic acid-templated transcription] Show all	432 aa 48.6 kDa	No	0
TRIP13-006 ENSP00000427528 ENST00000513435	H0YAL2 [Direct mapping] Pachytene checkpoint protein 2 homolog Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005524 [ATP binding] Show all	249 aa 28.1 kDa	No	0