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TRIP13

GENERAL INFORMATION

Gene name

 TRIP13

Gene description

 Thyroid hormone receptor interactor 13

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (testis)
GTEx:Tissue enriched (testis)
FANTOM5:Tissue enriched (testis)

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression mainly in testis.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 2 antibodies.
HPA005727 , HPA053093
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)

GENE INFORMATION

Gene name

 TRIP13 (HGNC Symbol)

Synonyms

 16E1BP

Description

 Thyroid hormone receptor interactor 13 (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein that interacts with thyroid hormone receptors, also known as hormone-dependent transcription factors. The gene product interacts specifically with the ligand binding domain. This gene is one of several that may play a role in early-stage non-small cell lung cancer. [provided by RefSeq, Oct 2009]

Chromosome

 5

Cytoband

 p15.33

Chromosome location (bp)

 892643 - 919357

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000071539 (version 83.38)

Entrez gene

 9319

UniProt

 Q15645 (UniProt - Evidence at protein level)

neXtProt

 NX_Q15645

Antibodypedia

 TRIP13 antibodies

PROTEIN BROWSER
TRIP13-001
TRIP13-006

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TRIP13-001
ENSP00000166345
ENST00000166345
Q15645 [Direct mapping]
Pachytene checkpoint protein 2 homolog
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0001556 [oocyte maturation]
GO:0001673 [male germ cell nucleus]
GO:0003712 [transcription cofactor activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0006302 [double-strand break repair]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007130 [synaptonemal complex assembly]
GO:0007131 [reciprocal meiotic recombination]
GO:0007141 [male meiosis I]
GO:0007144 [female meiosis I]
GO:0007283 [spermatogenesis]
GO:0007286 [spermatid development]
GO:0042802 [identical protein binding]
GO:0048477 [oogenesis]
GO:1903506 [regulation of nucleic acid-templated transcription]
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 432 aa
48.6 kDa 		No 0
TRIP13-006
ENSP00000427528
ENST00000513435
H0YAL2 [Direct mapping]
Pachytene checkpoint protein 2 homolog
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0005524 [ATP binding]
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 249 aa
28.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.