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ARHGAP15

CANCER ATLAS

Gene description

 Rho GTPase activating protein 15

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA032125

GENE INFORMATION

Gene name

 ARHGAP15 (HGNC Symbol)

Synonyms

 BM046

Description

 Rho GTPase activating protein 15 (HGNC Symbol)

Entrez gene summary

 RHO GTPases (see ARHA; MIM 165390) regulate diverse biologic processes, and their activity is regulated by RHO GTPase-activating proteins (GAPs), such as ARHGAP15 (Seoh et al., 2003 [PubMed 12650940]).[supplied by OMIM, Mar 2008]

Chromosome

 2

Cytoband

Chromosome location (bp)

 143091362 - 143768352

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000075884 (version 83.38)

Entrez gene

 55843

UniProt

 Q53QZ3 (UniProt - Evidence at protein level)

neXtProt

 NX_Q53QZ3

Antibodypedia

 ARHGAP15 antibodies

PROTEIN BROWSER
ARHGAP15-001
ARHGAP15-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ARHGAP15-001
ENSP00000295095
ENST00000295095
Q53QZ3 [Direct mapping]
Rho GTPase-activating protein 15
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005096 [GTPase activator activity]
GO:0005829 [cytosol]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0008360 [regulation of cell shape]
GO:0016020 [membrane]
GO:0043547 [positive regulation of GTPase activity]
GO:0051056 [regulation of small GTPase mediated signal transduction]
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 475 aa
54.5 kDa 		No 0
ARHGAP15-002
ENSP00000386560
ENST00000409869
B8ZZK0 [Direct mapping]
Rho GTPase-activating protein 15
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 138 aa
15.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.