Cell atlas - ARHGAP15 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

ARHGAP15

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Golgi apparatus
	Nucleoplasm
	Vesicles

Human cell
	Golgi Apparatus
	Nucleoplasm
	Vesicles

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	ARHGAP15
Gene description	Rho GTPase activating protein 15
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the Golgi apparatus & vesicles. In addition localized to the nucleoplasm.
RNA cell category	Cell line enhanced (HL-60, THP-1, HEL, MOLT-4, U-698, NB-4)
Protein evidence	Evidence at protein level
Main location	Localized to the Golgi apparatus (uncertain), Vesicles (uncertain)
Additional location	In addition localized to the Nucleoplasm (uncertain)

DATA RELIABILITY
Reliability score	Uncertain based on 1 antibody. HPA032125
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (HL-60, THP-1, HEL, MOLT-4, U-698, NB-4) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the Golgi apparatus & vesicles. In addition localized to the nucleoplasm.

Main location

Golgi apparatus (uncertain), Vesicles (uncertain)

Additional location

Nucleoplasm (uncertain)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA032125	A-431	Nucleoplasm
	HPA032125	A-431	Golgi apparatus
	HPA032125	U-2 OS	Golgi apparatus
	HPA032125	U-2 OS	Vesicles
	HPA032125	U-251 MG	Golgi apparatus
	HPA032125	U-251 MG	Vesicles

GENE INFORMATION
Gene name	ARHGAP15 (HGNC Symbol)
Synonyms	BM046
Description	Rho GTPase activating protein 15 (HGNC Symbol)
Entrez gene summary	RHO GTPases (see ARHA; MIM 165390) regulate diverse biologic processes, and their activity is regulated by RHO GTPase-activating proteins (GAPs), such as ARHGAP15 (Seoh et al., 2003 [PubMed 12650940]).[supplied by OMIM, Mar 2008]
Chromosome	2
Cytoband
Chromosome location (bp)	143091362 - 143768352
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000075884 (version 83.38)
Entrez gene	55843
UniProt	Q53QZ3 (UniProt - Evidence at protein level)
neXtProt	NX_Q53QZ3
Antibodypedia	ARHGAP15 antibodies

PROTEIN BROWSER

ARHGAP15-001	ARHGAP15-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ARHGAP15-001 ENSP00000295095 ENST00000295095	Q53QZ3 [Direct mapping] Rho GTPase-activating protein 15 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0005829 [cytosol] GO:0007165 [signal transduction] GO:0007264 [small GTPase mediated signal transduction] GO:0008360 [regulation of cell shape] GO:0016020 [membrane] GO:0043547 [positive regulation of GTPase activity] GO:0051056 [regulation of small GTPase mediated signal transduction] Show all	475 aa 54.5 kDa	No	0
ARHGAP15-002 ENSP00000386560 ENST00000409869	B8ZZK0 [Direct mapping] Rho GTPase-activating protein 15 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		138 aa 15.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.