Expression of SLC35C2 in cancer - Summary

CANCER ATLAS

Gene description

Solute carrier family 35 (GDP-fucose transporter), member C2

Protein class

Predicted membrane proteins, Transporters

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA027011

GENE INFORMATION
Gene name	SLC35C2 (HGNC Symbol)
Synonyms	bA394O2.1, C20orf5, CGI-15, OVCOV1
Description	Solute carrier family 35 (GDP-fucose transporter), member C2 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the triose-phosphate transporter protein family. This gene is regulated by oxygen tension, is induced in hypoxic trophoblast cells, and is overexpressed in ovarian cancer. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Jul 2013]
Chromosome	20
Cytoband	q13.12
Chromosome location (bp)	46345980 - 46364458
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000080189 (version 83.38)
Entrez gene	51006
UniProt	Q9NQQ7 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NQQ7
Antibodypedia	SLC35C2 antibodies

PROTEIN BROWSER

SLC35C2-001	SLC35C2-002	SLC35C2-003	SLC35C2-006	SLC35C2-007	SLC35C2-013	SLC35C2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC35C2-001 ENSP00000439974 ENST00000543605	Q9NQQ7 [Direct mapping] Solute carrier family 35 member C2 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment] GO:0005794 [Golgi apparatus] GO:0005801 [cis-Golgi network] GO:0015297 [antiporter activity] GO:0015786 [UDP-glucose transport] GO:0016021 [integral component of membrane] GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane] GO:0098656 [anion transmembrane transport] Show all	344 aa 38.2 kDa	No	>9
SLC35C2-002 ENSP00000243896 ENST00000243896	Q9NQQ7 [Direct mapping] Solute carrier family 35 member C2 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment] GO:0005794 [Golgi apparatus] GO:0005801 [cis-Golgi network] GO:0015297 [antiporter activity] GO:0015786 [UDP-glucose transport] GO:0016021 [integral component of membrane] GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane] GO:0098656 [anion transmembrane transport] Show all	365 aa 40.4 kDa	No	>9
SLC35C2-003 ENSP00000361301 ENST00000372227	Q9NQQ7 [Direct mapping] Solute carrier family 35 member C2 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment] GO:0005794 [Golgi apparatus] GO:0005801 [cis-Golgi network] GO:0015297 [antiporter activity] GO:0015786 [UDP-glucose transport] GO:0016021 [integral component of membrane] GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane] GO:0098656 [anion transmembrane transport] Show all	365 aa 40.4 kDa	No	>9
SLC35C2-006 ENSP00000397142 ENST00000420518	Q5JW04 [Direct mapping] Solute carrier family 35 member C2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0015297 [antiporter activity] GO:0015786 [UDP-glucose transport] GO:0016021 [integral component of membrane] GO:0098656 [anion transmembrane transport] Show all	196 aa 21.8 kDa	No	2
SLC35C2-007 ENSP00000415736 ENST00000424568	Q5JW03 [Direct mapping] Solute carrier family 35 member C2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0015297 [antiporter activity] GO:0015786 [UDP-glucose transport] GO:0016021 [integral component of membrane] GO:0098656 [anion transmembrane transport] Show all	158 aa 17.7 kDa	No	2
SLC35C2-013 ENSP00000361304 ENST00000372230	Q9NQQ7 [Direct mapping] Solute carrier family 35 member C2 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment] GO:0005794 [Golgi apparatus] GO:0005801 [cis-Golgi network] GO:0015297 [antiporter activity] GO:0015786 [UDP-glucose transport] GO:0016021 [integral component of membrane] GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane] GO:0098656 [anion transmembrane transport] Show all	365 aa 40.4 kDa	No	>9
SLC35C2-201 ENSP00000318960 ENST00000317734	Q9NQQ7 [Direct mapping] Solute carrier family 35 member C2 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment] GO:0005794 [Golgi apparatus] GO:0005801 [cis-Golgi network] GO:0010629 [negative regulation of gene expression] GO:0015297 [antiporter activity] GO:0015786 [UDP-glucose transport] GO:0016021 [integral component of membrane] GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane] GO:0036065 [fucosylation] GO:0036066 [protein O-linked fucosylation] GO:0045747 [positive regulation of Notch signaling pathway] GO:0098656 [anion transmembrane transport] Show all	394 aa 43.4 kDa	No	>9