Cell atlas - SLC35C2 - The Human Protein Atlas

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SLC35C2

TISSUE

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CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Golgi apparatus
	Nucleoplasm

Human cell
	Golgi Apparatus
	Nucleoplasm

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GENERAL INFORMATION
Gene name	SLC35C2
Gene description	Solute carrier family 35 (GDP-fucose transporter), member C2
Protein class	Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the Golgi apparatus. In addition localized to the nucleoplasm.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Golgi apparatus (supported)
Additional location	In addition localized to the Nucleoplasm (approved)
Single-cell variation	Single-cell variation in protein expression observed.

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA027011
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the Golgi apparatus. In addition localized to the nucleoplasm.

Main location

Golgi apparatus (supported)

Additional location

Nucleoplasm (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA027011	A549	Nucleoplasm
	HPA027011	A549	Golgi apparatus	Intensity
	HPA027011	MCF7	Nucleoplasm
	HPA027011	MCF7	Golgi apparatus
	HPA027011	U-2 OS	Golgi apparatus

GENE INFORMATION
Gene name	SLC35C2 (HGNC Symbol)
Synonyms	bA394O2.1, C20orf5, CGI-15, OVCOV1
Description	Solute carrier family 35 (GDP-fucose transporter), member C2 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the triose-phosphate transporter protein family. This gene is regulated by oxygen tension, is induced in hypoxic trophoblast cells, and is overexpressed in ovarian cancer. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Jul 2013]
Chromosome	20
Cytoband	q13.12
Chromosome location (bp)	46345980 - 46364458
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000080189 (version 83.38)
Entrez gene	51006
UniProt	Q9NQQ7 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NQQ7
Antibodypedia	SLC35C2 antibodies

PROTEIN BROWSER

SLC35C2-001	SLC35C2-002	SLC35C2-003	SLC35C2-006	SLC35C2-007	SLC35C2-013	SLC35C2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC35C2-001 ENSP00000439974 ENST00000543605	Q9NQQ7 [Direct mapping] Solute carrier family 35 member C2 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment] GO:0005794 [Golgi apparatus] GO:0005801 [cis-Golgi network] GO:0015297 [antiporter activity] GO:0015786 [UDP-glucose transport] GO:0016021 [integral component of membrane] GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane] GO:0098656 [anion transmembrane transport] Show all	344 aa 38.2 kDa	No	>9
SLC35C2-002 ENSP00000243896 ENST00000243896	Q9NQQ7 [Direct mapping] Solute carrier family 35 member C2 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment] GO:0005794 [Golgi apparatus] GO:0005801 [cis-Golgi network] GO:0015297 [antiporter activity] GO:0015786 [UDP-glucose transport] GO:0016021 [integral component of membrane] GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane] GO:0098656 [anion transmembrane transport] Show all	365 aa 40.4 kDa	No	>9
SLC35C2-003 ENSP00000361301 ENST00000372227	Q9NQQ7 [Direct mapping] Solute carrier family 35 member C2 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment] GO:0005794 [Golgi apparatus] GO:0005801 [cis-Golgi network] GO:0015297 [antiporter activity] GO:0015786 [UDP-glucose transport] GO:0016021 [integral component of membrane] GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane] GO:0098656 [anion transmembrane transport] Show all	365 aa 40.4 kDa	No	>9
SLC35C2-006 ENSP00000397142 ENST00000420518	Q5JW04 [Direct mapping] Solute carrier family 35 member C2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0015297 [antiporter activity] GO:0015786 [UDP-glucose transport] GO:0016021 [integral component of membrane] GO:0098656 [anion transmembrane transport] Show all	196 aa 21.8 kDa	No	2
SLC35C2-007 ENSP00000415736 ENST00000424568	Q5JW03 [Direct mapping] Solute carrier family 35 member C2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0015297 [antiporter activity] GO:0015786 [UDP-glucose transport] GO:0016021 [integral component of membrane] GO:0098656 [anion transmembrane transport] Show all	158 aa 17.7 kDa	No	2
SLC35C2-013 ENSP00000361304 ENST00000372230	Q9NQQ7 [Direct mapping] Solute carrier family 35 member C2 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment] GO:0005794 [Golgi apparatus] GO:0005801 [cis-Golgi network] GO:0015297 [antiporter activity] GO:0015786 [UDP-glucose transport] GO:0016021 [integral component of membrane] GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane] GO:0098656 [anion transmembrane transport] Show all	365 aa 40.4 kDa	No	>9
SLC35C2-201 ENSP00000318960 ENST00000317734	Q9NQQ7 [Direct mapping] Solute carrier family 35 member C2 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment] GO:0005794 [Golgi apparatus] GO:0005801 [cis-Golgi network] GO:0010629 [negative regulation of gene expression] GO:0015297 [antiporter activity] GO:0015786 [UDP-glucose transport] GO:0016021 [integral component of membrane] GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane] GO:0036065 [fucosylation] GO:0036066 [protein O-linked fucosylation] GO:0045747 [positive regulation of Notch signaling pathway] GO:0098656 [anion transmembrane transport] Show all	394 aa 43.4 kDa	No	>9

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.