We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Malignant tissues exhibited moderate to strong nuclear and cytoplasmic immunoreactivity.
GENE INFORMATION
Gene name
TNPO1 (HGNC Symbol)
Synonyms
IPO2, KPNB2, MIP, MIP1, TRN
Description
Transportin 1 (HGNC Symbol)
Entrez gene summary
This gene encodes the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in two transcript variants encoding different proteins. [provided by RefSeq, Jul 2008]
Transporters Transporter channels and pores Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Transporters Transporter channels and pores Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)