Expression of MAPRE3 in cancer - Summary

CANCER ATLAS

Gene description

Microtubule-associated protein, RP/EB family, member 3

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA009263

GENE INFORMATION
Gene name	MAPRE3 (HGNC Symbol)
Synonyms	EB3, RP3
Description	Microtubule-associated protein, RP/EB family, member 3 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a member of the RP/EB family of genes. The protein localizes to the cytoplasmic microtubule network and binds APCL, a homolog of the adenomatous polyposis coli tumor suppressor gene. [provided by RefSeq, Jul 2008]
Chromosome	2
Cytoband	p23.3
Chromosome location (bp)	26970612 - 27027196
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000084764 (version 83.38)
Entrez gene	22924
UniProt	Q9UPY8 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UPY8
Antibodypedia	MAPRE3 antibodies

PROTEIN BROWSER

MAPRE3-001	MAPRE3-002	MAPRE3-003	MAPRE3-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MAPRE3-001 ENSP00000233121 ENST00000233121	Q9UPY8 [Direct mapping] Microtubule-associated protein RP/EB family member 3 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005874 [microtubule] GO:0005881 [cytoplasmic microtubule] GO:0007067 [mitotic nuclear division] GO:0008017 [microtubule binding] GO:0015630 [microtubule cytoskeleton] GO:0030496 [midbody] GO:0035371 [microtubule plus-end] GO:0045737 [positive regulation of cyclin-dependent protein serine/threonine kinase activity] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0048471 [perinuclear region of cytoplasm] GO:0051301 [cell division] GO:1903033 [positive regulation of microtubule plus-end binding] Show all	281 aa 32 kDa	No	0
MAPRE3-002 ENSP00000383915 ENST00000405074	Q9UPY8 [Direct mapping] Microtubule-associated protein RP/EB family member 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005881 [cytoplasmic microtubule] GO:0007067 [mitotic nuclear division] GO:0008017 [microtubule binding] GO:0015630 [microtubule cytoskeleton] GO:0030496 [midbody] GO:0045737 [positive regulation of cyclin-dependent protein serine/threonine kinase activity] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0048471 [perinuclear region of cytoplasm] GO:0051301 [cell division] Show all	266 aa 30.4 kDa	No	0
MAPRE3-003 ENSP00000391705 ENST00000458529	C9JB30 [Direct mapping] Microtubule-associated protein RP/EB family member 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0008017 [microtubule binding] Show all	218 aa 24.6 kDa	No	0
MAPRE3-004 ENSP00000385715 ENST00000402218	Q9UPY8 [Direct mapping] Microtubule-associated protein RP/EB family member 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005881 [cytoplasmic microtubule] GO:0007067 [mitotic nuclear division] GO:0008017 [microtubule binding] GO:0015630 [microtubule cytoskeleton] GO:0030496 [midbody] GO:0045737 [positive regulation of cyclin-dependent protein serine/threonine kinase activity] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0048471 [perinuclear region of cytoplasm] GO:0051301 [cell division] Show all	266 aa 30.4 kDa	No	0