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MAPRE3

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GENERAL INFORMATION

Gene name

 MAPRE3

Gene description

 Microtubule-associated protein, RP/EB family, member 3

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Localized to the cytosol.

RNA cell category

 Mixed

Protein evidence

 Evidence at protein level

Main location

 Localized to the Cytosol (supported)

DATA RELIABILITY

Reliability score

 Supported based on 1 antibody.
HPA009263
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ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Localized to the cytosol.

Main location

 Cytosol (supported)

 

 

 
Toggle channels
Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA009263 A-431 Cytosol
HPA009263 U-2 OS Cytosol
HPA009263 U-251 MG Cytosol

GENE INFORMATION

Gene name

 MAPRE3 (HGNC Symbol)

Synonyms

 EB3, RP3

Description

 Microtubule-associated protein, RP/EB family, member 3 (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is a member of the RP/EB family of genes. The protein localizes to the cytoplasmic microtubule network and binds APCL, a homolog of the adenomatous polyposis coli tumor suppressor gene. [provided by RefSeq, Jul 2008]

Chromosome

 2

Cytoband

 p23.3

Chromosome location (bp)

 26970612 - 27027196

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000084764 (version 83.38)

Entrez gene

 22924

UniProt

 Q9UPY8 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9UPY8

Antibodypedia

 MAPRE3 antibodies

PROTEIN BROWSER
MAPRE3-001
MAPRE3-002
MAPRE3-003
MAPRE3-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MAPRE3-001
ENSP00000233121
ENST00000233121
Q9UPY8 [Direct mapping]
Microtubule-associated protein RP/EB family member 3
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005874 [microtubule]
GO:0005881 [cytoplasmic microtubule]
GO:0007067 [mitotic nuclear division]
GO:0008017 [microtubule binding]
GO:0015630 [microtubule cytoskeleton]
GO:0030496 [midbody]
GO:0035371 [microtubule plus-end]
GO:0045737 [positive regulation of cyclin-dependent protein serine/threonine kinase activity]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051301 [cell division]
GO:1903033 [positive regulation of microtubule plus-end binding]
Show all
 281 aa
32 kDa 		No 0
MAPRE3-002
ENSP00000383915
ENST00000405074
Q9UPY8 [Direct mapping]
Microtubule-associated protein RP/EB family member 3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005881 [cytoplasmic microtubule]
GO:0007067 [mitotic nuclear division]
GO:0008017 [microtubule binding]
GO:0015630 [microtubule cytoskeleton]
GO:0030496 [midbody]
GO:0045737 [positive regulation of cyclin-dependent protein serine/threonine kinase activity]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051301 [cell division]
Show all
 266 aa
30.4 kDa 		No 0
MAPRE3-003
ENSP00000391705
ENST00000458529
C9JB30 [Direct mapping]
Microtubule-associated protein RP/EB family member 3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0008017 [microtubule binding]
Show all
 218 aa
24.6 kDa 		No 0
MAPRE3-004
ENSP00000385715
ENST00000402218
Q9UPY8 [Direct mapping]
Microtubule-associated protein RP/EB family member 3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005881 [cytoplasmic microtubule]
GO:0007067 [mitotic nuclear division]
GO:0008017 [microtubule binding]
GO:0015630 [microtubule cytoskeleton]
GO:0030496 [midbody]
GO:0045737 [positive regulation of cyclin-dependent protein serine/threonine kinase activity]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051301 [cell division]
Show all
 266 aa
30.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.