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A majority of the cancer tissues displayed weak to moderate nuclear positivity. Gliomas, lymphomas, prostate, stomach, pancreatic and liver cancers were generally negative.
GENE INFORMATION
Gene name
ZBTB25 (HGNC Symbol)
Synonyms
C14orf51, KUP, ZNF46
Description
Zinc finger and BTB domain containing 25 (HGNC Symbol)
P24278 [Direct mapping] Zinc finger and BTB domain-containing protein 25
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Predicted intracellular proteins Plasma proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0010467 [gene expression] GO:0046872 [metal ion binding]
G3V2K3 [Direct mapping] Zinc finger and BTB domain-containing protein 25
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Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014)
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GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0006357 [regulation of transcription from RNA polymerase II promoter]
G3V351 [Direct mapping] Zinc finger and BTB domain containing 25, isoform CRA_b; Zinc finger and BTB domain-containing protein 25
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Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014)
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GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0046872 [metal ion binding]
