Fields »
ABOUT
HELP
BLOG
KIF4A

GENERAL INFORMATION

Gene name

 KIF4A

Gene description

 Kinesin family member 4A

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Mixed
FANTOM5:Tissue enhanced (testis, tonsil)

Protein evidence

 Evidence at protein level

Protein expression

 Nuclear expression in bone marrow with cytoplasmic and nuclear expression in most cells.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Caution, targets protein from more than one gene.

Reliability score

 Approved based on 2 antibodies.
HPA034745 , HPA034746
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Bone marrow

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (testis, tonsil)

GENE INFORMATION

Gene name

 KIF4A (HGNC Symbol)

Synonyms

 FLJ12530, FLJ12655, FLJ14204, FLJ20631, HSA271784, KIF4, KIF4-G1, MRX100

Description

 Kinesin family member 4A (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the kinesin 4 subfamily of kinesin related proteins. The encoded protein is an ATP dependent microtubule-based motor protein that is involved in the intracellular transport of membranous organelles. This protein also associates with condensed chromosome arms and may be involved in maintaining chromosome integrity during mitosis. This protein may also be involved in the organization of the central spindle prior to cytokinesis. A pseudogene of this gene is found on chromosome X.[provided by RefSeq, Mar 2010]

Chromosome

 X

Cytoband

 q13.1

Chromosome location (bp)

 70290090 - 70420832

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000090889 (version 83.38)

Entrez gene

 24137

UniProt

 O95239 (UniProt - Evidence at protein level)

neXtProt

 NX_O95239

Antibodypedia

 KIF4A antibodies

PROTEIN BROWSER
KIF4A-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
KIF4A-001
ENSP00000363524
ENST00000374403
O95239 [Direct mapping]
Chromosome-associated kinesin KIF4A
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000281 [mitotic cytokinesis]
GO:0003677 [DNA binding]
GO:0003777 [microtubule motor activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005654 [nucleoplasm]
GO:0005694 [chromosome]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005871 [kinesin complex]
GO:0005876 [spindle microtubule]
GO:0006996 [organelle organization]
GO:0007018 [microtubule-based movement]
GO:0007411 [axon guidance]
GO:0007596 [blood coagulation]
GO:0008017 [microtubule binding]
GO:0008089 [anterograde axon cargo transport]
GO:0008152 [metabolic process]
GO:0016020 [membrane]
GO:0016363 [nuclear matrix]
GO:0016887 [ATPase activity]
GO:0019886 [antigen processing and presentation of exogenous peptide antigen via MHC class II]
GO:0030496 [midbody]
GO:0051256 [mitotic spindle midzone assembly]
Show all
 1232 aa
139.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.