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A few cases of malignant carcinoids, liver and renal cancers exhibited weak to moderate cytoplasmic immunoreactivity. Malignant cells in general were negative.
GENE INFORMATION
Gene name
APOH (HGNC Symbol)
Synonyms
B2G1, BG
Description
Apolipoprotein H (beta-2-glycoprotein I) (HGNC Symbol)
Entrez gene summary
Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections. [provided by RefSeq, Jul 2008]