Expression of SLC17A6 in cancer - Summary

CANCER ATLAS

Gene description

Solute carrier family 17 (vesicular glutamate transporter), member 6

Protein class

Predicted membrane proteins, Transporters

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA039226	CAB037130

GENE INFORMATION
Gene name	SLC17A6 (HGNC Symbol)
Synonyms	DNPI, VGLUT2
Description	Solute carrier family 17 (vesicular glutamate transporter), member 6 (HGNC Symbol)
Entrez gene summary
Chromosome	11
Cytoband	p14.3
Chromosome location (bp)	22338097 - 22379503
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000091664 (version 83.38)
Entrez gene	57084
UniProt	Q9P2U8 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9P2U8
Antibodypedia	SLC17A6 antibodies

PROTEIN BROWSER

SLC17A6-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC17A6-001 ENSP00000263160 ENST00000263160	Q9P2U8 [Direct mapping] Vesicular glutamate transporter 2 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0005313 [L-glutamate transmembrane transporter activity] GO:0006811 [ion transport] GO:0006814 [sodium ion transport] GO:0006836 [neurotransmitter transport] GO:0015293 [symporter activity] GO:0016021 [integral component of membrane] GO:0030054 [cell junction] GO:0030672 [synaptic vesicle membrane] GO:0043005 [neuron projection] GO:0055085 [transmembrane transport] GO:0089711 [L-glutamate transmembrane transport] Show all	582 aa 64.4 kDa	No	>9