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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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HAUS4
  • TISSUE

  • premium

    CELL

  • CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

CANCER ATLAS

Gene description

HAUS augmin-like complex, subunit 4

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA029803

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

A majority of malignant cells showed weak to moderate cytoplasmic and membranous positivity. Few cases of malignant carcinoids and prostate cancers were strongly stained. Several cases of squamous cell carcinomas, malignant lymphomas and renal cancers were negative.

GENE INFORMATION

Gene name

HAUS4 (HGNC Symbol)

Synonyms

C14orf94, FLJ20424

Description

HAUS augmin-like complex, subunit 4 (HGNC Symbol)

Entrez gene summary

This gene encodes a subunit of the centrosome complex termed the human augmin complex. The encoded protein localizes to the spindle microtubules and may play a role in mitotic spindle assembly and maintenance of centrosome integrity during cell division. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009]

Chromosome

14

Cytoband

q11.2

Chromosome location (bp)

22946228 - 22957161

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000092036 (version 83.38)

Entrez gene

54930

UniProt

Q9H6D7 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H6D7

Antibodypedia

HAUS4 antibodies

PROTEIN BROWSER

«
HAUS4-001
HAUS4-002
HAUS4-003
HAUS4-004
HAUS4-005
HAUS4-006
HAUS4-011
HAUS4-012
HAUS4-013
HAUS4-014
HAUS4-020
HAUS4-021
HAUS4-201
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HAUS4-001
ENSP00000452260
ENST00000490506
Q9H6D7 [Direct mapping]
HAUS augmin-like complex subunit 4
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005819 [spindle]
GO:0005874 [microtubule]
GO:0007067 [mitotic nuclear division]
GO:0051225 [spindle assembly]
GO:0051297 [centrosome organization]
GO:0051301 [cell division]
GO:0070652 [HAUS complex]
Show all
239 aa
28.1 kDa
No 0
HAUS4-002
ENSP00000452239
ENST00000555367
Q9H6D7 [Direct mapping]
HAUS augmin-like complex subunit 4
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005819 [spindle]
GO:0005874 [microtubule]
GO:0007067 [mitotic nuclear division]
GO:0051225 [spindle assembly]
GO:0051297 [centrosome organization]
GO:0051301 [cell division]
GO:0070652 [HAUS complex]
Show all
318 aa
37.2 kDa
No 0
HAUS4-003
ENSP00000206474
ENST00000206474
Q9H6D7 [Direct mapping]
HAUS augmin-like complex subunit 4
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005819 [spindle]
GO:0005874 [microtubule]
GO:0007067 [mitotic nuclear division]
GO:0051225 [spindle assembly]
GO:0051297 [centrosome organization]
GO:0051301 [cell division]
GO:0070652 [HAUS complex]
Show all
363 aa
42.4 kDa
No 0
HAUS4-004
ENSP00000343473
ENST00000347758
Q9H6D7 [Direct mapping]
HAUS augmin-like complex subunit 4
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005819 [spindle]
GO:0005874 [microtubule]
GO:0007067 [mitotic nuclear division]
GO:0051225 [spindle assembly]
GO:0051297 [centrosome organization]
GO:0051301 [cell division]
GO:0070652 [HAUS complex]
Show all
237 aa
27.8 kDa
No 0
HAUS4-005
ENSP00000342776
ENST00000342454
Q9H6D7 [Direct mapping]
HAUS augmin-like complex subunit 4
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005819 [spindle]
GO:0005874 [microtubule]
GO:0007067 [mitotic nuclear division]
GO:0051225 [spindle assembly]
GO:0051297 [centrosome organization]
GO:0051301 [cell division]
GO:0070652 [HAUS complex]
Show all
318 aa
37.2 kDa
No 0
HAUS4-006
ENSP00000451018
ENST00000555986
Q9H6D7 [Direct mapping]
HAUS augmin-like complex subunit 4
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005819 [spindle]
GO:0005874 [microtubule]
GO:0007067 [mitotic nuclear division]
GO:0051225 [spindle assembly]
GO:0051297 [centrosome organization]
GO:0051301 [cell division]
GO:0070652 [HAUS complex]
Show all
318 aa
37.2 kDa
No 0
HAUS4-011
ENSP00000450680
ENST00000554406
G3V2I5 [Direct mapping]
HAUS augmin-like complex subunit 4
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
17 aa
1.9 kDa
No 0
HAUS4-012
ENSP00000452058
ENST00000557591
G3V4X7 [Direct mapping]
HAUS augmin-like complex subunit 4
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0051225 [spindle assembly]
GO:0051297 [centrosome organization]
GO:0070652 [HAUS complex]
Show all
160 aa
18.4 kDa
No 0
HAUS4-013
ENSP00000450612
ENST00000553420
H0YJ09 [Direct mapping]
HAUS augmin-like complex subunit 4
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0051225 [spindle assembly]
GO:0051297 [centrosome organization]
GO:0070652 [HAUS complex]
Show all
147 aa
16.8 kDa
No 0
HAUS4-014
ENSP00000452595
ENST00000556915
G3V5Z2 [Direct mapping]
HAUS augmin-like complex subunit 4
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0051225 [spindle assembly]
GO:0051297 [centrosome organization]
GO:0070652 [HAUS complex]
Show all
152 aa
17.5 kDa
No 0
HAUS4-020
ENSP00000452261
ENST00000554516
G3V5A5 [Direct mapping]
HAUS augmin-like complex subunit 4
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0051225 [spindle assembly]
GO:0051297 [centrosome organization]
GO:0070652 [HAUS complex]
Show all
187 aa
21.7 kDa
No 0
HAUS4-021
ENSP00000452165
ENST00000555040
G3V541 [Direct mapping]
HAUS augmin-like complex subunit 4
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0051225 [spindle assembly]
GO:0051297 [centrosome organization]
GO:0070652 [HAUS complex]
Show all
279 aa
32.2 kDa
No 0
HAUS4-201
ENSP00000441026
ENST00000541587
Q9H6D7 [Direct mapping]
HAUS augmin-like complex subunit 4
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005819 [spindle]
GO:0005874 [microtubule]
GO:0007067 [mitotic nuclear division]
GO:0051225 [spindle assembly]
GO:0051297 [centrosome organization]
GO:0051301 [cell division]
GO:0070652 [HAUS complex]
Show all
363 aa
42.4 kDa
No 0

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