Expression of TBL1Y in cancer - Summary - The Human Protein Atlas

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TBL1Y

TISSUE

CELL

CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

CANCER ATLAS

Gene description

Transducin (beta)-like 1, Y-linked

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA060073

GENE INFORMATION
Gene name	TBL1Y (HGNC Symbol)
Synonyms	TBL1
Description	Transducin (beta)-like 1, Y-linked (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This gene is highly similar to TBL1X gene in nucleotide sequence and protein sequence, but the TBL1X gene is located on chromosome X and this gene is on chromosome Y. This gene has three alternatively spliced transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Chromosome	Y
Cytoband	p11.2
Chromosome location (bp)	6910686 - 7091683
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000092377 (version 83.38)
Entrez gene	90665
UniProt	Q9BQ87 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9BQ87
Antibodypedia	TBL1Y antibodies

PROTEIN BROWSER

TBL1Y-001	TBL1Y-002	TBL1Y-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TBL1Y-001 ENSP00000372499 ENST00000383032	Q9BQ87 [Direct mapping] F-box-like/WD repeat-containing protein TBL1Y A0A024R189 [Target identity:100%; Query identity:100%] Transducin (Beta)-like 1Y-linked, isoform CRA_a Show all	Predicted intracellular proteins Show all	GO:0000118 [histone deacetylase complex] GO:0003714 [transcription corepressor activity] GO:0005515 [protein binding] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0016575 [histone deacetylation] Show all	522 aa 56.7 kDa	No	0
TBL1Y-002 ENSP00000347289 ENST00000355162	Q9BQ87 [Direct mapping] F-box-like/WD repeat-containing protein TBL1Y A0A024R189 [Target identity:100%; Query identity:100%] Transducin (Beta)-like 1Y-linked, isoform CRA_a Show all	Predicted intracellular proteins Show all	GO:0000118 [histone deacetylase complex] GO:0003714 [transcription corepressor activity] GO:0005515 [protein binding] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0016575 [histone deacetylation] Show all	522 aa 56.7 kDa	No	0
TBL1Y-003 ENSP00000328879 ENST00000346432	Q9BQ87 [Direct mapping] F-box-like/WD repeat-containing protein TBL1Y A0A024R189 [Target identity:100%; Query identity:100%] Transducin (Beta)-like 1Y-linked, isoform CRA_a Show all	Predicted intracellular proteins Show all	GO:0000118 [histone deacetylase complex] GO:0003714 [transcription corepressor activity] GO:0005515 [protein binding] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0016575 [histone deacetylation] Show all	522 aa 56.7 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.