Tissue expression of TBL1Y - Summary - The Human Protein Atlas

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TBL1Y

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	TBL1Y
Gene description	Transducin (beta)-like 1, Y-linked
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (prostate, thyroid gland)
GTEx:	Tissue enhanced (thyroid gland)
FANTOM5:	Tissue enhanced (pancreas, thyroid gland)

Protein evidence

Evidence at protein level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA060073
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (prostate, thyroid gland)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (thyroid gland)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (pancreas, thyroid gland)

GENE INFORMATION
Gene name	TBL1Y (HGNC Symbol)
Synonyms	TBL1
Description	Transducin (beta)-like 1, Y-linked (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This gene is highly similar to TBL1X gene in nucleotide sequence and protein sequence, but the TBL1X gene is located on chromosome X and this gene is on chromosome Y. This gene has three alternatively spliced transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Chromosome	Y
Cytoband	p11.2
Chromosome location (bp)	6910686 - 7091683
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000092377 (version 83.38)
Entrez gene	90665
UniProt	Q9BQ87 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9BQ87
Antibodypedia	TBL1Y antibodies

PROTEIN BROWSER

TBL1Y-001	TBL1Y-002	TBL1Y-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TBL1Y-001 ENSP00000372499 ENST00000383032	Q9BQ87 [Direct mapping] F-box-like/WD repeat-containing protein TBL1Y A0A024R189 [Target identity:100%; Query identity:100%] Transducin (Beta)-like 1Y-linked, isoform CRA_a Show all	Predicted intracellular proteins Show all	GO:0000118 [histone deacetylase complex] GO:0003714 [transcription corepressor activity] GO:0005515 [protein binding] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0016575 [histone deacetylation] Show all	522 aa 56.7 kDa	No	0
TBL1Y-002 ENSP00000347289 ENST00000355162	Q9BQ87 [Direct mapping] F-box-like/WD repeat-containing protein TBL1Y A0A024R189 [Target identity:100%; Query identity:100%] Transducin (Beta)-like 1Y-linked, isoform CRA_a Show all	Predicted intracellular proteins Show all	GO:0000118 [histone deacetylase complex] GO:0003714 [transcription corepressor activity] GO:0005515 [protein binding] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0016575 [histone deacetylation] Show all	522 aa 56.7 kDa	No	0
TBL1Y-003 ENSP00000328879 ENST00000346432	Q9BQ87 [Direct mapping] F-box-like/WD repeat-containing protein TBL1Y A0A024R189 [Target identity:100%; Query identity:100%] Transducin (Beta)-like 1Y-linked, isoform CRA_a Show all	Predicted intracellular proteins Show all	GO:0000118 [histone deacetylase complex] GO:0003714 [transcription corepressor activity] GO:0005515 [protein binding] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0016575 [histone deacetylation] Show all	522 aa 56.7 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.