Expression of RANBP1 in cancer - Summary

CANCER ATLAS

Gene description

RAN binding protein 1

Protein class

Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

CAB046463

GENE INFORMATION
Gene name	RANBP1 (HGNC Symbol)
Synonyms	HTF9A
Description	RAN binding protein 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein that forms a complex with Ras-related nuclear protein (Ran) and metabolizes guanoside triphosphate (GTP). This complex participates in the regulation of the cell cycle by controlling transport of proteins and nucleic acids into the nucleus. There are multiple pseudogenes for this gene on chromosomes 9, 12, 17, and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Chromosome	22
Cytoband	q11.21
Chromosome location (bp)	20115938 - 20127357
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000099901 (version 83.38)
Entrez gene	5902
UniProt	P43487 (UniProt - Evidence at protein level)
neXtProt	NX_P43487
Antibodypedia	RANBP1 antibodies

PROTEIN BROWSER

RANBP1-001	RANBP1-004	RANBP1-006	RANBP1-007	RANBP1-008	RANBP1-009	RANBP1-012	RANBP1-015	RANBP1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RANBP1-001 ENSP00000384925 ENST00000402752	P43487 [Direct mapping] Ran-specific GTPase-activating protein Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005092 [GDP-dissociation inhibitor activity] GO:0005096 [GTPase activator activity] GO:0005634 [nucleus] GO:0005635 [nuclear envelope] GO:0005737 [cytoplasm] GO:0007165 [signal transduction] GO:0008536 [Ran GTPase binding] GO:0016032 [viral process] GO:0043547 [positive regulation of GTPase activity] GO:0046907 [intracellular transport] GO:0050790 [regulation of catalytic activity] Show all	200 aa 23.2 kDa	No	0
RANBP1-004 ENSP00000404724 ENST00000432879	C9JDM3 [Direct mapping] Ran-specific GTPase-activating protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005622 [intracellular] GO:0046907 [intracellular transport] Show all	166 aa 18.9 kDa	No	0
RANBP1-006 ENSP00000404126 ENST00000416427	C9JIC6 [Direct mapping] Ran-specific GTPase-activating protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005622 [intracellular] GO:0046907 [intracellular transport] Show all	53 aa 6.3 kDa	No	0
RANBP1-007 ENSP00000400940 ENST00000421656	C9JIC6 [Direct mapping] Ran-specific GTPase-activating protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005622 [intracellular] GO:0046907 [intracellular transport] Show all	53 aa 6.3 kDa	No	0
RANBP1-008 ENSP00000404298 ENST00000423859	C9JGV6 [Direct mapping] Ran-specific GTPase-activating protein Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005622 [intracellular] GO:0046907 [intracellular transport] Show all	205 aa 23.3 kDa	No	0
RANBP1-009 ENSP00000413502 ENST00000418705	C9JXG8 [Direct mapping] Ran-specific GTPase-activating protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005622 [intracellular] GO:0046907 [intracellular transport] Show all	145 aa 16.9 kDa	No	0
RANBP1-012 ENSP00000395472 ENST00000411892	C9JJ34 [Direct mapping] Ran-specific GTPase-activating protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005622 [intracellular] GO:0046907 [intracellular transport] Show all	163 aa 18.8 kDa	No	0
RANBP1-015 ENSP00000327583 ENST00000331821	P43487 [Direct mapping] Ran-specific GTPase-activating protein Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005092 [GDP-dissociation inhibitor activity] GO:0005096 [GTPase activator activity] GO:0005634 [nucleus] GO:0005635 [nuclear envelope] GO:0005737 [cytoplasm] GO:0007165 [signal transduction] GO:0008536 [Ran GTPase binding] GO:0016032 [viral process] GO:0043547 [positive regulation of GTPase activity] GO:0046907 [intracellular transport] GO:0050790 [regulation of catalytic activity] Show all	201 aa 23.3 kDa	No	0
RANBP1-201 ENSP00000401564 ENST00000430524	F6WQW2 [Direct mapping] Ran-specific GTPase-activating protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005813 [centrosome] GO:0007051 [spindle organization] GO:0010976 [positive regulation of neuron projection development] GO:0032838 [cell projection cytoplasm] GO:0035690 [cellular response to drug] GO:0046604 [positive regulation of mitotic centrosome separation] GO:0046907 [intracellular transport] GO:0051592 [response to calcium ion] GO:0072750 [cellular response to leptomycin B] GO:1904115 [axon cytoplasm] Show all	278 aa 31.9 kDa	No	0